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Anti-CD40 Antibody (1S713) is a Rabbit antibody targeting CD40. Anti-CD40 Antibody (1S713) can be used in ELISA,ELISA(Det).
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 20 μL | $92 | 7-10 days | |
| 100 μL | $268 | 7-10 days |
| Description | Anti-CD40 Antibody (1S713) is a Rabbit antibody targeting CD40. Anti-CD40 Antibody (1S713) can be used in ELISA,ELISA(Det). |
| Synonyms | TRAP, Tnfrsf5, T-BAM, p50, IMD3, Igm, HIGM1, gp39, CD40 molecule, TNF receptor superfamily member 5, Bp50, AI326936 |
| Ig Type | Rabbit IgG |
| Clone | 1S713 |
| Reactivity | Human |
| Specificity | Human CD40/TNFRSF5 No cross-reactivity in ELISA with Human CD27 / TNFRSF7 Mouse CD27 / TNFRSF7 Human CD30 / TNFRSF8 Human DR6 / TNFRSF21 Human CD137 / 4-1BB Human TNFRSF1B / CD120b Human HVEM / TNFRSF14 Mouse HVEM / TNFRSF14 Human RELT / TNFRSF19L |
| Application | |
| Recommended Dose | ELISA: 1:5000-1:10000; ELISA(Det): 1:1000-1:10000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human CD40 extracellular domain (rh CD40; TMPY-01181; NP_001241.1; Met 1-Arg 193). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | CD40, also known as TNFRSF5, is a member of the TNF receptor superfamily which are single transmembrane-spanning glycoproteins. CD40 protein plays an essential role in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. CD40 protein is expressed in B cells, dendritic cells, macrophages, endothelial cells, and several tumor cell lines. Defects in CD40 result in hyper-IgM immunodeficiency type 3 (HIGM3). In addition, CD40/CD40L interaction is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis.Cancer ImmunotherapyCo-stimulatory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint Detection: AntibodiesImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint Detection: FCM AntibodiesImmune Checkpoint Detection: ICC AntibodiesImmune Checkpoint Detection: IP AntibodiesImmune Checkpoint Detection: WB AntibodiesImmune Checkpoint ProteinsImmune Checkpoint TargetsImmunotherapyTargeted Therapy |
| Conjucates | Unconjugated |
| Others Formats | HRP |
| Antibody Types Available | 2 |
| Immunogen | Recombinant Protein: Human CD40 protein (TMPY-01181) |
| Antigen Species | Human |
| Biology Area | Cancer Drug Targets |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |

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