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Magnesium isoglycyrrhizinate hydrate (18α-Glycyrrhizic acid Magnesium hydrate) is an active ingredient derived from licorice with anti-inflammatory properties. It lowers alanine and aspartate aminotransferase activities and can be used in HIV-1 infection research.

| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 2 mg | $38 | - | In Stock | |
| 5 mg | $60 | - | In Stock | |
| 10 mg | $87 | - | In Stock | |
| 25 mg | $145 | - | In Stock | |
| 50 mg | $213 | - | In Stock | |
| 100 mg | $318 | - | In Stock |
| Description | Magnesium isoglycyrrhizinate hydrate (18α-Glycyrrhizic acid Magnesium hydrate) is an active ingredient derived from licorice with anti-inflammatory properties. It lowers alanine and aspartate aminotransferase activities and can be used in HIV-1 infection research. |
| In vivo | Magnesium isoglycyrrhizinate hydrate (15 or 45 mg/kg.d, i.p., 18 days) was effective in inhibiting ethanol-induced spermatogenic epithelial tissue division and degeneration of supporting cells and germ cells, and was protective against oxidative damage of testis. [1] Magnesium isoglycyrrhizinate hydrate (0.40 or 0.80 mg/kg/d) exerts anti-inflammatory activity through the NLRP3 inflammatome pathway and improves chronic obstructive pulmonary disease in rats ina rat model. [2] |
| Synonyms | Tianqingganmei, 18α-Glycyrrhizic acid Magnesium hydrate |
| Molecular Weight | 917.28 |
| Formula | C42H68MgO20 |
| Cas No. | 658701-67-8 |
| Smiles | C[C@]12[C@@](C(C=C3[C@]2(CC[C@@]4([C@]3([H])C[C@](C)(CC4)C(O)=O)C)C)=O)([H])[C@@]5([C@@](C(C)([C@H](CC5)O[C@@H]6[C@@H]([C@H]([C@@H]([C@H](O6)C([O-])=O)O)O)O[C@@H]7O[C@@H]([C@H]([C@@H]([C@H]7O)O)O)C([O-])=O)C)([H])CC1)C.[Mg+2].O.O.O.O |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||
| Solubility Information | H2O: 20 mg/mL (21.8 mM), when pH is adjusted to 9 with NH3·H2O. | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
H2O
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Dissolve 2 mg of the compound in 100 μL DMSO
to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO
stock solution to 400 μL PEG300
and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O
and mix thoroughly until a homogeneous solution is obtained.
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