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RES-701-1

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Catalog No. TP3073Cas No. 151308-34-8

RES-701-1 is a cyclic peptide consisting of 16 common L-amino acids. It acts as a specific antagonist of the ETB receptor. RES-701-1 inhibits the binding of 125I-ET-1 (125I-labeled endothelin (ET)-1) to the ETB receptor, with an IC50 value of 10 nM.

RES-701-1

RES-701-1

😃Good
Catalog No. TP3073Cas No. 151308-34-8
RES-701-1 is a cyclic peptide consisting of 16 common L-amino acids. It acts as a specific antagonist of the ETB receptor. RES-701-1 inhibits the binding of 125I-ET-1 (125I-labeled endothelin (ET)-1) to the ETB receptor, with an IC50 value of 10 nM.
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Product Introduction

Bioactivity
Description
RES-701-1 is a cyclic peptide consisting of 16 common L-amino acids. It acts as a specific antagonist of the ETB receptor. RES-701-1 inhibits the binding of 125I-ET-1 (125I-labeled endothelin (ET)-1) to the ETB receptor, with an IC50 value of 10 nM.
Targets&IC50
ETB:10 nM
Chemical Properties
Molecular Weight2043.16
FormulaC103H115N23O23
Cas No.151308-34-8
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice./Shipping at ambient temperature.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
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