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Hydroxysafflor yellow A

🥰Excellent
Catalog No. T3674Cas No. 78281-02-4
Alias Safflomin A, HSYA

Hydroxysafflor yellow A (Safflomin A) inhibits adipogenesis by increasing HSL promoter activities, effectively protects the liver from long-term alcohol injury by enhancing antioxidant capacity and inhibiting the expression of TGF-β, prevents steroid-induced avascular necrosis of the femoral head by inhibiting primary bone marrow-derived mesenchymal stromal cells, and exhibits anti-tumor effects.

Hydroxysafflor yellow A

Hydroxysafflor yellow A

🥰Excellent
Purity: 99.88%
Catalog No. T3674Alias Safflomin A, HSYACas No. 78281-02-4
Hydroxysafflor yellow A (Safflomin A) inhibits adipogenesis by increasing HSL promoter activities, effectively protects the liver from long-term alcohol injury by enhancing antioxidant capacity and inhibiting the expression of TGF-β, prevents steroid-induced avascular necrosis of the femoral head by inhibiting primary bone marrow-derived mesenchymal stromal cells, and exhibits anti-tumor effects.
Pack SizePriceAvailabilityQuantity
5 mg$37In Stock
10 mg$50In Stock
25 mg$78In Stock
50 mg$113In Stock
100 mg$163In Stock
200 mg$239In Stock
1 mL x 10 mM (in DMSO)$60In Stock
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Purity:99.88%
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Product Introduction

Bioactivity
Description
Hydroxysafflor yellow A (Safflomin A) inhibits adipogenesis by increasing HSL promoter activities, effectively protects the liver from long-term alcohol injury by enhancing antioxidant capacity and inhibiting the expression of TGF-β, prevents steroid-induced avascular necrosis of the femoral head by inhibiting primary bone marrow-derived mesenchymal stromal cells, and exhibits anti-tumor effects.
SynonymsSafflomin A, HSYA
Chemical Properties
Molecular Weight612.53
FormulaC27H32O16
Cas No.78281-02-4
SmilesOC1(C(O)=C(C(=O)C(C(/C=C/C2=CC=C(O)C=C2)=O)=C1O)[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O
Relative Density.1.851 g/cm3 (Predicted)
Storage & Solubility Information
Storagekeep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
H2O: 10 mg/mL (16.33 mM), Sonication is recommended.
DMSO: 50 mg/mL (81.63 mM), Sonication is recommended.
Solution Preparation Table
H2O/DMSO
1mg5mg10mg50mg
1 mM1.6326 mL8.1629 mL16.3257 mL81.6287 mL
5 mM0.3265 mL1.6326 mL3.2651 mL16.3257 mL
10 mM0.1633 mL0.8163 mL1.6326 mL8.1629 mL
DMSO
1mg5mg10mg50mg
20 mM0.0816 mL0.4081 mL0.8163 mL4.0814 mL
50 mM0.0327 mL0.1633 mL0.3265 mL1.6326 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
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Keywords

TGF-β/SmadTGFβTGFbeta/SmadTGF-betaTGFbetaTGF-b/SmadTGFbSmadInhibitorinhibitHydroxysafflor yellow A146087-19-6
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