Powder: -20°C for 3 years | In solvent: -80°C for 1 year
JNK-IN-12 (compound P2) is a mitochondrial-targeted JNK inhibitor with an IC50 value of 66.3 nM, comprising a mitochondrial-specific cell-penetrating peptide linked to SP600125, a selective JNK inhibitor. It selectively impedes mitochondrial JNK phosphorylation without inhibiting nuclear JNK signaling and has been shown to ameliorate Parkinson's disease (PD) symptoms in both in vitro and in vivo studies [1].
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Description | JNK-IN-12 (compound P2) is a mitochondrial-targeted JNK inhibitor with an IC50 value of 66.3 nM, comprising a mitochondrial-specific cell-penetrating peptide linked to SP600125, a selective JNK inhibitor. It selectively impedes mitochondrial JNK phosphorylation without inhibiting nuclear JNK signaling and has been shown to ameliorate Parkinson's disease (PD) symptoms in both in vitro and in vivo studies [1]. |
Molecular Weight | 1091.35 |
Formula | C56H82N16O7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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JNK-IN-12 MAPK JNK inhibitor inhibit