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Anti-IL-1F8 Antibody (8T581) is a Rabbit antibody targeting IL-1F8. Anti-IL-1F8 Antibody (8T581) can be used in ELISA.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 μL | $268 | 7-10 days |
Description | Anti-IL-1F8 Antibody (8T581) is a Rabbit antibody targeting IL-1F8. Anti-IL-1F8 Antibody (8T581) can be used in ELISA. |
Alias | interleukin 36, β, interleukin 36, beta, IL36B, IL-1H2, IL1H2, IL-1F8, IL1F8, IL1-ETA, FILI-(ETA), FIL1H, FIL1-(ETA), FIL1 |
Ig Type | Monoclonal Rabbit IgG |
Clone | 8T581 |
Reactivity | Mouse |
Application | ELISA |
Recommended Dose | ELISA: 1:5000-1:10000 |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse IL36B / IL1F8 (TMPY-02583; Q9D6Z6; Met1-Lys183). |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | Interleukin-1 family member 8(IL1F8) also known as IL36B, is a member of the interleukin 1(IL-1) cytokine family. IL1F8 may contain a 12-stranded beta-trefoil structure. Until recently, the IL-1 family of cytokines includes four members, with three having pro-inflammatory effects such as IL1F8 and the fourth member being an IL-1 receptor antagonist (IL-1Ra). IL-1 family members exert their effects through binding to receptors that belong to the IL-1 receptor (IL-1R) family. IL1F8 exerts proinflammatory effects in primary human joint cells. Joint and serum IL-1F8 protein levels did not correlate with inflammation, but they were high in some human serum samples tested, including samples from patients with rheumatoid arthritis. IL1F8 also activated NK-κB. |
Conjucates | Unconjugated |
Immunogen | Recombinant Mouse IL36B / IL1F8 protein (TMPY-02583) |
Antigen Species | Mouse |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
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