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Rosnilimab

(Synonyms: ANB-030, ANB030) Copy Product Info
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Synonyms: ANB-030, ANB030

Catalog No. T80619 Copy Product Info
Purity: 95%
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Rosnilimab (ANB030) is a programmed cell death protein 1 (PD-1) agonist that can inhibit antigen-driven T cell proliferation, reduce the secretion of pro-inflammatory cytokines, and deplete CD4 and CD8 T cell populations characterized by high PD-1 expression, thereby enabling its use in the research of various inflammatory diseases such as colitis and rheumatoid arthritis.
Rosnilimab
Cas No. 2412764-40-8
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Pack SizePriceUSA StockGlobal StockQuantity
1 mg$247-In Stock
5 mg$645-In Stock
10 mg$987-In Stock
25 mg$1,460-In Stock
50 mg$1,970-In Stock
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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With extensive experience in compound synthesis, we can provide rapid custom synthesis services for this product according to your research needs.
For research use only—not for human use. No sales to individuals. Use as intended only.
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Batch Information

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Purity:98.9% (SDS-PAGE); 98.7% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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Product Introduction

Bioactivity
Description
Rosnilimab (ANB030) is a programmed cell death protein 1 (PD-1) agonist that can inhibit antigen-driven T cell proliferation, reduce the secretion of pro-inflammatory cytokines, and deplete CD4 and CD8 T cell populations characterized by high PD-1 expression, thereby enabling its use in the research of various inflammatory diseases such as colitis and rheumatoid arthritis.
SynonymsANB-030, ANB030
Reactivity
Human
Verified Activity
Immobilized Human PD-1 Protein (His) (TMPY-00897) at 1 μg/mL (100 μL/well) can bind Rosnilimab. The EC50 is 6.00 ng/mL.
Rosnilimab
Application
Functional assay
Antibody Type
Monoclonal
FormulationSupplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Gene ID
Uniprot ID
TargetPDCD1/PD-1/CD279
Chemical Properties
Molecular Weight146.57 kDa
Cas No.2412764-40-8
Antibody Information
IsotypeHuman IgG1 kappa
Recommended Isotype Control
Storage & Solubility Information
StorageStore at low temperature -20°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Related Tags: Rosnilimab chemical structure | Rosnilimab molecular weight