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Incensole acetate

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Catalog No. TN1764Cas No. 34701-53-6

Incensole acetate is a natural product and TRPV3 agonist that induces calcium influx in HEK293 cells expressing TRPV3 channels. It modifies c-Fos activation in the mouse brain, exhibits anti-anxiety effects, and possesses anti-inflammatory properties.

Incensole acetate

Incensole acetate

🥰Excellent
Catalog No. TN1764Cas No. 34701-53-6
Incensole acetate is a natural product and TRPV3 agonist that induces calcium influx in HEK293 cells expressing TRPV3 channels. It modifies c-Fos activation in the mouse brain, exhibits anti-anxiety effects, and possesses anti-inflammatory properties.
Pack SizePriceAvailabilityQuantity
1 mg$52In Stock
5 mg$110In Stock
10 mg$190In Stock
25 mg$379In Stock
50 mg$569In Stock
1 mL x 10 mM (in DMSO)$85In Stock
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Product Introduction

Bioactivity
Description
Incensole acetate is a natural product and TRPV3 agonist that induces calcium influx in HEK293 cells expressing TRPV3 channels. It modifies c-Fos activation in the mouse brain, exhibits anti-anxiety effects, and possesses anti-inflammatory properties.
Targets&IC50
HEK293 cells:2.2 μM
In vitro
Methods: To investigate the preventive effects on Aβ25-35-induced neurotoxicity in homo sapiens olfactory bulb neural stem cells (hOBNSCs), hOBNSCs were pretreated with Incensole acetate (100 μM) for 4 hours prior to Aβ25-35 treatment. Cell viability was assessed using the MTT assay. 
Results: Aβ25-35 significantly reduced cell viability, whereas Incensole acetate pretreatment markedly restored cell viability.[1]
Chemical Properties
Molecular Weight348.52
FormulaC22H36O3
Cas No.34701-53-6
Relative Density.0.99 g/cm3 (Predicted)
ColorTransparent
AppearanceOil
Storage & Solubility Information
Storagekeep away from direct sunlight,keep away from moisture,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 80 mg/mL (229.54 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.8693 mL14.3464 mL28.6928 mL143.4638 mL
5 mM0.5739 mL2.8693 mL5.7386 mL28.6928 mL
10 mM0.2869 mL1.4346 mL2.8693 mL14.3464 mL
20 mM0.1435 mL0.7173 mL1.4346 mL7.1732 mL
50 mM0.0574 mL0.2869 mL0.5739 mL2.8693 mL
100 mM0.0287 mL0.1435 mL0.2869 mL1.4346 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Keywords

NFkB
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