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JAK3/BTK-IN-1

Catalog No. T9814 CAS 2674036-91-8

JAK3/ BTk-in-1 is a dual JAK3/BTK inhibitor that specifically targets and inhibits Janus kinase 3 (JAK3) and Bruton's tyrosine kinase (BTK), two important targets in autoimmune diseases. JAK3/ BTk-in-1 simultaneously inhibited the BTK/JAK3 signaling pathway, showing a synergistic effect. JAK3/ BTK-in-1 is a potential compound for the treatment of immune-related diseases, such as autoimmune diseases, certain types of cancer (including lymphoma and leukemia), and other diseases that may be characterized by an unbalanced immune response.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

JAK3/BTK-IN-1, CAS 2674036-91-8

Pack Size	Availability	Price/USD
1 mg	Synthesizing,6-8 weeks	$ 195.00
5 mg	Synthesizing,6-8 weeks	$ 448.00
10 mg	Synthesizing,6-8 weeks	$ 675.00
25 mg	Synthesizing,6-8 weeks	$ 1,154.00
50 mg	Synthesizing,6-8 weeks	$ 1,728.00
100 mg	Synthesizing,6-8 weeks	$ 2,595.00

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Molecular Weight	456.554
Formula	C25H28N8O
CAS No.	2674036-91-8

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Guobao Zhang, et al. Pyrimidopyrroles. Patent WO2021147952A1.

Related Products

Related compounds with same targets

(±)-Zanubrutinib JAK3/BTK-IN-1 Acalabrutinib enantiomer AS-1763 BTK inhibitor 1 (Compound 27) Naluzotan CHMFL-BTK-01 Spebrutinib besylate

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

JAK3/BTK-IN-1 2674036-91-8 JAK/STAT signaling Chromatin/Epigenetic Stem Cells Tyrosine Kinase/Adaptors Angiogenesis BTK JAK JAK3/BTK IN 1 JAK-3/BTK-IN-1 JAK3/BTKIN1 Inhibitor inhibitor inhibit

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.