Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Mitobronitol (Myelobromol; DBM) is a brominated analog of mannitol. Mitobronitol is an anticancer agent classified as an alkylating agent. Mitobronitol shows myelosuppression effect that significantly reduced risk for several complications of allogeneic bone marrow transplantation in accelerated chronic granulocytic leukemia [1] [2].
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 6-8 weeks | $ 1,520.00 | |
50 mg | 6-8 weeks | $ 1,980.00 | |
100 mg | 6-8 weeks | $ 2,500.00 |
Description | Mitobronitol (Myelobromol; DBM) is a brominated analog of mannitol. Mitobronitol is an anticancer agent classified as an alkylating agent. Mitobronitol shows myelosuppression effect that significantly reduced risk for several complications of allogeneic bone marrow transplantation in accelerated chronic granulocytic leukemia [1] [2]. |
In vivo | Mitobronitol (850 mg/kg; i.p.; single dose) enhances the proliferative response of spleen cells to mitogens and facilitates thymus regeneration in a mouse model. Utilizing female BALB-c mice aged 8-10 weeks, the study administered the compound intraperitoneally at doses of 850 mg/kg and 1500 mg/kg, suspended in 5% Tween 80 in saline. Results demonstrated that at 850 mg/kg, mitobronitol significantly improved spleen cell proliferation to mitogens. Moreover, at a higher dose of 1500 mg/kg, it expedited thymus regeneration, initiating restitution within 2 weeks and achieving substantial regeneration within 3 weeks, surpassing the outcomes observed in the control group. |
Molecular Weight | 307.97 |
Formula | C6H12Br2O4 |
CAS No. | 488-41-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Mitobronitol 488-41-5 inhibitor inhibit