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α-Conotoxin MrIC

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Catalog No. T80471Cas No. 1417816-41-1

α-Conotoxin MrIC is a biased agonist selective for the α7 nicotinic acetylcholine receptor (nAChR), with activation contingent upon the presence of type II positive allosteric modulators, such as PNU120596. It is utilized to investigate neurological disorders and delineate the pharmacological characteristics of the α7nAChR [1].

α-Conotoxin MrIC

α-Conotoxin MrIC

😃Good
Catalog No. T80471Cas No. 1417816-41-1
α-Conotoxin MrIC is a biased agonist selective for the α7 nicotinic acetylcholine receptor (nAChR), with activation contingent upon the presence of type II positive allosteric modulators, such as PNU120596. It is utilized to investigate neurological disorders and delineate the pharmacological characteristics of the α7nAChR [1].
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Product Introduction

Bioactivity
Description
α-Conotoxin MrIC is a biased agonist selective for the α7 nicotinic acetylcholine receptor (nAChR), with activation contingent upon the presence of type II positive allosteric modulators, such as PNU120596. It is utilized to investigate neurological disorders and delineate the pharmacological characteristics of the α7nAChR [1].
Chemical Properties
Molecular Weight1835.07
FormulaC74H111N23O24S4
Cas No.1417816-41-1
SequencePro-Glu-Cys-Cys-Thr-His-Pro-Ala-Cys-His-Val-Ser-Asn-Pro-Glu-Leu-Cys-NH2 (Disulfide bridge:Cys3-Cys9, Cys4-Cys17)
Sequence ShortPECCTHPACHVSNPELC-NH2 (Disulfide bridge:Cys3-Cys9, Cys4-Cys17)
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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