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1-Linoleoyl Glycerol

🥰Excellent
Catalog No. T10017Cas No. 2277-28-3
Alias Monolinolein, Glyceryl monolinoleate, Glycerol 1-monolinolate, 1-Linoleoyl-rac-glycerol

1-Linoleoyl Glycerol (Monolinolein) is fatty acid glycerol that has been isolated from Saururus Chinensis roots. The (R)-1-Linoleoyl Glycerol and (S)-1-Linoleoyl Glycerol exhibit Lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitory activities with IC50 values of 45.0 and 52.0 μM, respectively.

1-Linoleoyl Glycerol
Other Forms of 1-Linoleoyl Glycerol:
Glyceryl monolinoleateT2545726545-74-4
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1-Linoleoyl Glycerol

🥰Excellent
Purity: 99.56%
Catalog No. T10017Alias Monolinolein, Glyceryl monolinoleate, Glycerol 1-monolinolate, 1-Linoleoyl-rac-glycerolCas No. 2277-28-3
1-Linoleoyl Glycerol (Monolinolein) is fatty acid glycerol that has been isolated from Saururus Chinensis roots. The (R)-1-Linoleoyl Glycerol and (S)-1-Linoleoyl Glycerol exhibit Lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitory activities with IC50 values of 45.0 and 52.0 μM, respectively.
Pack SizePriceAvailabilityQuantity
25 mg$29In Stock
1 mL x 10 mM (in DMSO)$55In Stock
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Batch Information

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Purity:99.56%
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COA HPLC HNMR

Product Introduction

Bioactivity
Description
1-Linoleoyl Glycerol (Monolinolein) is fatty acid glycerol that has been isolated from Saururus Chinensis roots. The (R)-1-Linoleoyl Glycerol and (S)-1-Linoleoyl Glycerol exhibit Lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitory activities with IC50 values of 45.0 and 52.0 μM, respectively.
Targets&IC50
Lp-PLA2:45.0 μM((R)-1-Linoleoyl Glycerol), Lp-PLA2:52.0 μM((S)-1-Linoleoyl Glycerol)
SynonymsMonolinolein, Glyceryl monolinoleate, Glycerol 1-monolinolate, 1-Linoleoyl-rac-glycerol
Chemical Properties
Molecular Weight354.52
FormulaC21H38O4
Cas No.2277-28-3
SmilesCCCCCC=CCC=CCCCCCCCC(=O)OCC(O)CO
Relative Density.0.981 g/cm3
Storage & Solubility Information
Storagestore at low temperature | Pure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
Ethanol: 88 mg/mL (248.22 mM), Sonication is recommended.
DMSO: 88 mg/mL (248.22 mM), Sonication is recommended.
Solution Preparation Table
Ethanol/DMSO
1mg5mg10mg50mg
1 mM2.8207 mL14.1036 mL28.2072 mL141.0358 mL
5 mM0.5641 mL2.8207 mL5.6414 mL28.2072 mL
10 mM0.2821 mL1.4104 mL2.8207 mL14.1036 mL
20 mM0.1410 mL0.7052 mL1.4104 mL7.0518 mL
50 mM0.0564 mL0.2821 mL0.5641 mL2.8207 mL
100 mM0.0282 mL0.1410 mL0.2821 mL1.4104 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
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2 Enter the in vivo formulation:
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

PhospholipaseLp-PLA2Inhibitorinhibit1-Monolinolein1-Linoleoyl Glycerol1Linoleoyl Glycerol1 Linoleoyl Glycerol
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