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Bevifimod (Synonyms: PRTX-100)

Catalog No. T82893 Copy Product Info
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Bevifimod (PRTX-100), a highly purified variant of Staphylococcal protein A (SpA), is utilized in research on idiopathic thrombocytopenic purpura (ITP) [1] [2].

Bevifimod

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Catalog No. T82893
Synonyms PRTX-100

Bevifimod (PRTX-100), a highly purified variant of Staphylococcal protein A (SpA), is utilized in research on idiopathic thrombocytopenic purpura (ITP) [1] [2].

Bevifimod
Cas No. 2223113-32-2
Pack SizePriceUSA StockGlobal StockQuantity
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For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Bevifimod (PRTX-100), a highly purified variant of Staphylococcal protein A (SpA), is utilized in research on idiopathic thrombocytopenic purpura (ITP) [1] [2].
In vitro
Bevifimod (PRTX-100; concentrations of 250, 25, and 2.5 ng/mL; 48-hour exposure) inhibits the phagocytosis of W632-conditioned platelets by human monocytes in peripheral blood mononuclear cells (PBMC) [1].
In vivo
Bevifimod (PRTX-100; 2.5-250 µg/kg; i.v.; biweekly over 4 weeks) normalizes platelet counts within 1-2 weeks with no mortality in mice [2].
SynonymsPRTX-100
Reactivity
Human
Application
FACS
Functional assay
Antibody Type
Monoclonal
FormulationSupplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
TargetImmunoglobulin
Chemical Properties
Cas No.2223113-32-2
Storage & Solubility Information
Storage-20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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