Powder: -20°C for 3 years | In solvent: -80°C for 1 year
hSMG-1 inhibitor 11e is an effective and selective inhibitor of hSMG-1 (IC50 <0.05 nM) and can be used in studies about cancer treatment.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 157.00 | |
2 mg | In stock | $ 233.00 | |
5 mg | In stock | $ 397.00 | |
10 mg | In stock | $ 589.00 | |
25 mg | In stock | $ 945.00 | |
50 mg | In stock | $ 1,280.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 453.00 |
Description | hSMG-1 inhibitor 11e is an effective and selective inhibitor of hSMG-1 (IC50 <0.05 nM) and can be used in studies about cancer treatment. |
Targets&IC50 | mTOR:45 nM (IC50), PI3Kγ:92 nM (IC50), CDK1:32 μM (IC50), SMG-1 (human):<0.05 nM (IC50), PI3Kα:61 nM (IC50), CDK2:7.1 μM (IC50) |
In vitro | hSMG-1 inhibitor 11e exhibits an IC50 of 900-fold selectivity over mTOR (IC50 = 45 nM), PI3Kα/γ (IC50 = 61 nM), PI3Kγ (IC50 = 92 nM), CDK1(IC50 = 32 μM) and CDK2 (IC50 = 7.1 μM)[1]. |
Molecular Weight | 517.6 |
Formula | C26H27N7O3S |
CAS No. | 1402452-10-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 45 mg/mL (86.9 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
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