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Schnurri-3 inhibitor-1

Name: Schnurri-3 inhibitor-1
Brand: TargetMol
SKU: T60554
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T60554Cas No. 736154-60-2

Schnurri-3 inhibitor-1, a potent inhibitor of schnurri-3, is an essential regulator of bone formation in adults that can be used in osteoporosis research. Schnurri-3 inhibitor-1 can inhibit Shn3 with EF1alpha promoter in osteoblast cell line Shn3FFL (AC50 = 2.09 μM) [1].

Schnurri-3 inhibitor-1

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Purity: 99.97%

Catalog No. T60554Cas No. 736154-60-2

Pack Size	Price	USA Warehouse	Global Warehouse
50 mg	$41	In Stock	In Stock
100 mg	$70	In Stock	In Stock
200 mg	$98	-	In Stock
1 mL x 10 mM (in DMSO)	$29	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.97%

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COA HNMR LCMS

Product Introduction

Bioactivity

Description	Schnurri-3 inhibitor-1, a potent inhibitor of schnurri-3, is an essential regulator of bone formation in adults that can be used in osteoporosis research. Schnurri-3 inhibitor-1 can inhibit Shn3 with EF1alpha promoter in osteoblast cell line Shn3FFL (AC50 = 2.09 μM) [1].
In vitro	Schnurri-3 inhibitor-1 (0.195-26 μM; 48 h) exhibits moderate activity in HepG2 mammalian cells (AC50= 54.73 μM). Schnurri-3 inhibitor-1 (0-50 μM; 24 h) can inhibit Shn3 with EF1alpha promoter in SV40 large T antigen-transformed osteoblast cell line (Clone20-Shn3FFL, AC50= 2.09 μM)[1].

Chemical Properties

Molecular Weight	284.28
Formula	C₁₂H₁₀F₂N₂O₂S
Cas No.	736154-60-2
Smiles	Fc1ccc(cc1F)S(=O)(=O)NCc1ccncc1

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (175.88 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.5177 mL	17.5883 mL	35.1766 mL	175.8829 mL
5 mM	0.7035 mL	3.5177 mL	7.0353 mL	35.1766 mL
10 mM	0.3518 mL	1.7588 mL	3.5177 mL	17.5883 mL
20 mM	0.1759 mL	0.8794 mL	1.7588 mL	8.7941 mL
50 mM	0.0704 mL	0.3518 mL	0.7035 mL	3.5177 mL
100 mM	0.0352 mL	0.1759 mL	0.3518 mL	1.7588 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc