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Anti-Aconitase 1 Antibody (8K688)
(Synonyms: IRP1, IREBP1, IREBP, IREB1, HEL60, ACONS, aconitase 1, soluble) Copy Product Info
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Synonyms: IRP1, IREBP1, IREBP, IREB1, HEL60, ACONS, aconitase 1, soluble
Catalog No. TMAH-00016 Copy Product Info
🥰Excellent
Anti-Aconitase 1 Antibody (8K688) is an antibody targeting Aconitase 1. Anti-Aconitase 1 Antibody (8K688) can be used in ELISA,FCM,IF,WB.
Anti-Aconitase 1 Antibody
(8K688)
(8K688)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $209 | 7-10 days | 7-10 days | |
| 100 μL | $348 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-Aconitase 1 Antibody (8K688) is an antibody targeting Aconitase 1. Anti-Aconitase 1 Antibody (8K688) can be used in ELISA,FCM,IF,WB. |
| Synonyms | IRP1, IREBP1, IREBP, IREB1, HEL60, ACONS, aconitase 1, soluble |
| Ig Type | Rabbit IgG |
| Clone | 8K688 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB:1:500-1:2000; IF:1:50-1:200; FCM:1:50-1:200. |
| Antibody Type | Monoclonal |
| Subcellular Localization | Cytoplasm, cytosol. |
| Construction | Recombinant Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Bifunctional iron sensor that switches between 2 activities depending on iron availability. Iron deprivation, promotes its mRNA binding activity through which it regulates the expression of genes involved in iron uptake, sequestration and utilization. Binds to iron-responsive elements (IRES) in the untranslated region of target mRNAs preventing for instance the translation of ferritin and aminolevulinic acid synthase and stabilizing the transferrin receptor mRNA. Conversely, when cellular iron levels are high, binds a 4Fe-4S cluster which precludes RNA binding activity and promotes the aconitase activity, the isomerization of citrate to isocitrate via cis-aconitate. |
| Conjucates | Unconjugated |
| Immunogen | A synthetic peptide: Human ACO1 |
| Antigen Species | Human |
| Gene Name | ACO1 |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Epigenetics and Nuclear Signaling, Cancer, Cardiovascular, Metabolism, Signal transduction |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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