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Gotistobart

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Catalog No. T82268Cas No. 2226344-78-9
Alias ONC-392, ONC392, BNT316, BNT 316

Gotistobart (ONC-392; BNT 316) is a humanized monoclonal antibody targeting CTLA-4/CD152 that selectively depletes regulatory T cells (Tregs) in the tumor microenvironment and enhances immunotherapy efficacy, applicable for studying non-small cell lung cancer (NSCLC).

Gotistobart

Gotistobart

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Purity: 95%
Catalog No. T82268Alias ONC-392, ONC392, BNT316, BNT 316Cas No. 2226344-78-9
Gotistobart (ONC-392; BNT 316) is a humanized monoclonal antibody targeting CTLA-4/CD152 that selectively depletes regulatory T cells (Tregs) in the tumor microenvironment and enhances immunotherapy efficacy, applicable for studying non-small cell lung cancer (NSCLC).
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$247-In Stock
5 mg$619-In Stock
10 mg$993-In Stock
25 mg$1,470-In Stock
50 mg$1,990-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:95%
Appearance:Liquid
Color:Transparent
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Product Introduction

Bioactivity
Description
Gotistobart (ONC-392; BNT 316) is a humanized monoclonal antibody targeting CTLA-4/CD152 that selectively depletes regulatory T cells (Tregs) in the tumor microenvironment and enhances immunotherapy efficacy, applicable for studying non-small cell lung cancer (NSCLC).
SynonymsONC-392, ONC392, BNT316, BNT 316
Reactivity
Human
Application
FACS
Functional assay
Antibody Type
Monoclonal
FormulationSupplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Uniprot ID
TargetCTLA-4
Chemical Properties
Cas No.2226344-78-9
Antibody Information
IsotypeYTE-SA-EAKA
Storage & Solubility Information
Storagestore at low temperature | store at -20°C | Shipping with blue ice/Shipping at ambient temperature.

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