Popular Searches
Diphenyleneiodonium chlorideEpacadostatGilteritinibDinaciclibRo-3306
TargetMol | Star Product
Wikimole
TargetMol | New Product
New Product
TargetMol | Compound Library
Compound Library
Contact UsQuotation
Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty
Proceed to checkoutContinue shopping
TOPRelated productsBioactivityChemical infoStorage&SolubilityCalculator

CHK1-IN-4 hydrochloride

🥰Excellent
Catalog No. T10792L
Alias CHK1-IN-4 hydrochloride(2120398-41-4 Free base)

CHK1-IN-4 hydrochloride is a potent inhibitor of checkpoint kinase 1 (chk1). CHK1-IN-4 hydrochloride potently inhibits chk1 phosphorylation in the tumor cells. CHK1-IN-4 hydrochloride has anti-tumor activity.

CHK1-IN-4 hydrochloride
Other Forms of CHK1-IN-4 hydrochloride:
CHK1-IN-4T107922120398-41-4
Backorder
View details

CHK1-IN-4 hydrochloride

🥰Excellent
Purity: 99.29%
Catalog No. T10792LAlias CHK1-IN-4 hydrochloride(2120398-41-4 Free base)
CHK1-IN-4 hydrochloride is a potent inhibitor of checkpoint kinase 1 (chk1). CHK1-IN-4 hydrochloride potently inhibits chk1 phosphorylation in the tumor cells. CHK1-IN-4 hydrochloride has anti-tumor activity.
Pack SizePriceAvailabilityQuantity
1 mg$197In Stock
5 mg$478In Stock
10 mg$654In Stock
25 mg$990In Stock
50 mg$1,330In Stock
100 mg$1,750In Stock
Add to Cart
Add to Quotation
Bulk & Custom
This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.
Questions
View More

Batch Information

Select Batch
Purity:99.29%
Contact us for more batch information

Resource Download

COA LCMS IC HNMR

Product Introduction

Bioactivity
Description
CHK1-IN-4 hydrochloride is a potent inhibitor of checkpoint kinase 1 (chk1). CHK1-IN-4 hydrochloride potently inhibits chk1 phosphorylation in the tumor cells. CHK1-IN-4 hydrochloride has anti-tumor activity.
In vivo
CHK1-IN-4 hydrochloride (40 mg/kg, IV, twice a week) could enhance anti-tumor growth activity of CPT1 in the tumor model[1].
SynonymsCHK1-IN-4 hydrochloride(2120398-41-4 Free base)
Chemical Properties
Molecular Weight480.75
FormulaC18H19BrClN7O2
SmilesCl.COc1cc(Br)cc(OCCCN)c1-c1cc(Nc2cnc(cn2)C#N)n[nH]1
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 5 mg/mL (10.4 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.0801 mL10.4004 mL20.8008 mL104.0042 mL
5 mM0.4160 mL2.0801 mL4.1602 mL20.8008 mL
10 mM0.2080 mL1.0400 mL2.0801 mL10.4004 mL

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

CHK1-IN-4 HydrochlorideChk12120398-41-4 Free base2120398-41-4
Related Tags: buy CHK1-IN-4 hydrochloride | purchase CHK1-IN-4 hydrochloride | CHK1-IN-4 hydrochloride cost | order CHK1-IN-4 hydrochloride | CHK1-IN-4 hydrochloride chemical structure | CHK1-IN-4 hydrochloride in vivo | CHK1-IN-4 hydrochloride formula | CHK1-IN-4 hydrochloride molecular weight
TargetMol | Logo

Copyright © 2015-2025 TargetMol Chemicals Inc. All Rights Reserved.