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Indican

🥰Excellent
Catalog No. T19866Cas No. 487-60-5
Alias NSC-87517, NSC87517, NSC 87517, Indoxyl-β-D-glucoside, 3-Indoxyl-beta-D-glucopyranoside

Indican (Indoxyl-β-D-glucoside) is a natural protective compound that is used to protect the liver.

Indican

Indican

🥰Excellent
Purity: 99.92%
Catalog No. T19866Alias NSC-87517, NSC87517, NSC 87517, Indoxyl-β-D-glucoside, 3-Indoxyl-beta-D-glucopyranosideCas No. 487-60-5
Indican (Indoxyl-β-D-glucoside) is a natural protective compound that is used to protect the liver.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 mg$31In StockIn Stock
50 mg$40In StockIn Stock
100 mg$56In StockIn Stock
1 mL x 10 mM (in DMSO)$29In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information

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Purity:99.92%
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COA HNMR HPLC

Product Introduction

Bioactivity
Description
Indican (Indoxyl-β-D-glucoside) is a natural protective compound that is used to protect the liver.
In vitro
Oral single doses of Indican at 20, 40 mg/kg increase the systemic exposure of MTX and MRT by inhibiting multiple anion transporters including OAT 1, OAT 3, and MRP 4 via the major metabolite indoxyl sulfate (IS) [3].
SynonymsNSC-87517, NSC87517, NSC 87517, Indoxyl-β-D-glucoside, 3-Indoxyl-beta-D-glucopyranoside
Chemical Properties
Molecular Weight295.29
FormulaC14H17NO6
Cas No.487-60-5
SmilesOC[C@H]1O[C@@H](Oc2c[nH]c3ccccc23)[C@H](O)[C@@H](O)[C@@H]1O
Relative Density.1.562 g/cm3 (Predicted)
ColorYellow
AppearanceSolid
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
H2O: 8 mg/mL (27.09 mM), Sonication is recommended.
DMSO: 88 mg/mL (298.01 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 3.3 mg/mL (11.18 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
H2O/DMSO
1mg5mg10mg50mg
1 mM3.3865 mL16.9325 mL33.8650 mL169.3251 mL
5 mM0.6773 mL3.3865 mL6.7730 mL33.8650 mL
10 mM0.3387 mL1.6933 mL3.3865 mL16.9325 mL
20 mM0.1693 mL0.8466 mL1.6933 mL8.4663 mL
DMSO
1mg5mg10mg50mg
50 mM0.0677 mL0.3387 mL0.6773 mL3.3865 mL
100 mM0.0339 mL0.1693 mL0.3387 mL1.6933 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
mg/kg
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μL
2 Enter the in vivo formulation:
% DMSO
%
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Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

uremictransportertoxinsulfateorganicOAT3OAT1MRP4InhibitorinhibitIndoxyl-beta-D-glucosideIndoxyl-b-D-glucosideindoxylindirubinIndicanglycoside, indoxyldyesindigoanion3-Indoxyl-β-D-glucopyranoside3-Indoxyl-b-D-glucopyranoside
Related Tags: buy Indican | purchase Indican | Indican cost | order Indican | Indican chemical structure | Indican in vitro | Indican formula | Indican molecular weight
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