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BW 755C

Name: BW 755C
Brand: TargetMol
SKU: T22054
Price: 59 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T22054Cas No. 66000-40-6

BW 755C is a dual inhibitor of 5-lipoxygenase (5-LO) and cyclooxygenase (COX) pathways.

BW 755C

🥰Excellent

Purity: 96.52%

Catalog No. T22054Cas No. 66000-40-6

BW 755C is a dual inhibitor of 5-lipoxygenase (5-LO) and cyclooxygenase (COX) pathways.

Pack Size	Price	USA Warehouse	Global Warehouse
5 mg	$59	In Stock	In Stock
10 mg	$79	In Stock	In Stock
25 mg	$123	In Stock	In Stock
50 mg	$176	In Stock	In Stock
100 mg	$257	In Stock	In Stock
1 mL x 10 mM (in DMSO)	$68	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

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Purity:96.52%

Appearance:Solid

Color:Yellow

Resource Download

COA HNMR HPLC

Product Introduction

Bioactivity

Description	BW 755C is a dual inhibitor of 5-lipoxygenase (5-LO) and cyclooxygenase (COX) pathways.
Targets&IC50	COX-1: 0.65 μg/ml, COX-2: 1.2 μg/ml, 5-LOX: 0.75 μM
In vitro	BW 755C is approximately equipotent inhibitors of COX-1 and COX-2 in intact cells.

Chemical Properties

Molecular Weight	229.2
Formula	C₁₀H₁₀F₃N₃
Cas No.	66000-40-6
Smiles	C(F)(F)(F)C=1C=C(C=CC1)N2N=C(N)CC2
Relative Density.	1.40 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

Ethanol: 20 mg/mL (87.26 mM), Sonication is recommended.

DMSO: 25 mg/mL (109.08 mM), Sonication is recommended.

Solution Preparation Table

Ethanol/DMSO

	1mg	5mg	10mg	50mg
1 mM	4.3630 mL	21.8150 mL	43.6300 mL	218.1501 mL
5 mM	0.8726 mL	4.3630 mL	8.7260 mL	43.6300 mL
10 mM	0.4363 mL	2.1815 mL	4.3630 mL	21.8150 mL
20 mM	0.2182 mL	1.0908 mL	2.1815 mL	10.9075 mL
50 mM	0.0873 mL	0.4363 mL	0.8726 mL	4.3630 mL

DMSO

	1mg	5mg	10mg	50mg
100 mM	0.0436 mL	0.2182 mL	0.4363 mL	2.1815 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc