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Axatilimab (Synonyms: UCB6352, UCB 6352, SNDX-6352, SNDX6352, INCA-034176, INCA034176)

Catalog No. T76915 Copy Product Info
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Axatilimab (SNDX-6352) is a human IgG4 antibody targeting the colony-stimulating factor 1 receptor (CSF-1R), which can be used for the study of immune system disorders and respiratory diseases.

Axatilimab

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Catalog No. T76915
Synonyms UCB6352, UCB 6352, SNDX-6352, SNDX6352, INCA-034176, INCA034176

Axatilimab (SNDX-6352) is a human IgG4 antibody targeting the colony-stimulating factor 1 receptor (CSF-1R), which can be used for the study of immune system disorders and respiratory diseases.

Axatilimab
Cas No. 2155851-88-8
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Pack SizePriceUSA StockGlobal StockQuantity
1 mg$197In StockIn Stock
5 mg$516In StockIn Stock
10 mg$828-In Stock
25 mg$1,230-In Stock
50 mg$1,650-In Stock
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Batch Information

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Purity:97.9% (SDS-PAGE); 97% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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Product Introduction

Bioactivity
Description
Axatilimab (SNDX-6352) is a human IgG4 antibody targeting the colony-stimulating factor 1 receptor (CSF-1R), which can be used for the study of immune system disorders and respiratory diseases.
In vitro
Axatilimab affects the migration, proliferation, differentiation and survival of monocytes and macrophages by binding to CSF-1R and blocking the activation of its two known ligands, CSF-1 and IL-34. [1]
SynonymsUCB6352, UCB 6352, SNDX-6352, SNDX6352, INCA-034176, INCA034176
Reactivity
Human
Application
Functional assay
Antibody Type
Monoclonal
FormulationSupplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Gene ID
Uniprot ID
TargetCSF1R/M-CSFR/CD115
Chemical Properties
Molecular Weight147.17 kDa
Cas No.2155851-88-8
Antibody Information
IsotypeHuman IgG1 kappa
Recommended Isotype Control
Storage & Solubility Information
Storagestore at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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