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Anti-AGER Antibody (7O93)

😃Good
Catalog No. TMAY-03322
Alias SCARJ1, RAGE, AGER

Anti-AGER Antibody (7O93) is a Rabbit antibody targeting AGER. Anti-AGER Antibody (7O93) can be used in ELISA.

Anti-AGER Antibody (7O93)

Anti-AGER Antibody (7O93)

😃Good
Catalog No. TMAY-03322Alias SCARJ1, RAGE, AGER
Anti-AGER Antibody (7O93) is a Rabbit antibody targeting AGER. Anti-AGER Antibody (7O93) can be used in ELISA.
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100 μL$268 7-10 days
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Product Introduction

Bioactivity
Description
Anti-AGER Antibody (7O93) is a Rabbit antibody targeting AGER. Anti-AGER Antibody (7O93) can be used in ELISA.
AliasSCARJ1, RAGE, AGER
Ig Type
Monoclonal Rabbit IgG
Clone
7O93
Reactivity
Mouse
Application
ELISA
Recommended Dose
ELISA: 1:5000-1:10000
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Mouse RAGE / AGER (rM RAGE / AGER; TMPY-01675; NP_031451.2; Met1-Ala342).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundReceptor for Advanced Glycosylation End Products (RAGE, or AGER) is a member of the immunoglobulin super-family transmembrane proteins, as a signal transduction receptor which binds advanced glycation endproducts, certain members of the S100/calgranulin family of proteins, high mobility group box 1 (HMGB1), advanced oxidation protein products, and amyloid (beta-sheet fibrils). Initial studies investigating the role of RAGE in renal dysfunction focused on diabetes, neurodegenerative disorders, and inflammatory responses. However, RAGE also has roles in the pathogenesis of renal disorders that are not associated with diabetes, such as obesity-related glomerulopathy, doxorubicin-induced nephropathy, hypertensive nephropathy, lupus nephritis, renal amyloidosis, and ischemic renal injuries. RAGE represents an important factor in innate immunity against pathogens, but it also interacts with endogenous ligands, resulting in chronic inflammation. RAGE signaling has been implicated in multiple human illnesses, including atherosclerosis, arthritis, Alzheimer's disease, atherosclerosis and aging associated diseases.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Mouse RAGE / AGER protein (TMPY-01675)
Antigen Species
Mouse
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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