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Anti-AGER Antibody (7O93)
😃Good
Catalog No. TMAY-03322
Alias SCARJ1, RAGE, AGER
Anti-AGER Antibody (7O93) is a Rabbit antibody targeting AGER. Anti-AGER Antibody (7O93) can be used in ELISA.
Anti-AGER Antibody (7O93)
Anti-AGER Antibody (7O93)
😃Good
Catalog No. TMAY-03322Alias SCARJ1, RAGE, AGER
Anti-AGER Antibody (7O93) is a Rabbit antibody targeting AGER. Anti-AGER Antibody (7O93) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $268 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-AGER Antibody (7O93) is a Rabbit antibody targeting AGER. Anti-AGER Antibody (7O93) can be used in ELISA. |
| Synonyms | SCARJ1, RAGE, AGER |
| Ig Type | Rabbit IgG |
| Clone | 7O93 |
| Reactivity | Mouse |
| Specificity | Mouse RAGE Has cross-reactivity in ELISA with Human AGER |
| Application | |
| Recommended Dose | ELISA: 1:5000-1:10000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse RAGE / AGER (rM RAGE / AGER; TMPY-01675; NP_031451.2; Met1-Ala342). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Receptor for Advanced Glycosylation End Products (RAGE, or AGER) is a member of the immunoglobulin super-family transmembrane proteins, as a signal transduction receptor which binds advanced glycation endproducts, certain members of the S100/calgranulin family of proteins, high mobility group box 1 (HMGB1), advanced oxidation protein products, and amyloid (beta-sheet fibrils). Initial studies investigating the role of RAGE in renal dysfunction focused on diabetes, neurodegenerative disorders, and inflammatory responses. However, RAGE also has roles in the pathogenesis of renal disorders that are not associated with diabetes, such as obesity-related glomerulopathy, doxorubicin-induced nephropathy, hypertensive nephropathy, lupus nephritis, renal amyloidosis, and ischemic renal injuries. RAGE represents an important factor in innate immunity against pathogens, but it also interacts with endogenous ligands, resulting in chronic inflammation. RAGE signaling has been implicated in multiple human illnesses, including atherosclerosis, arthritis, Alzheimer's disease, atherosclerosis and aging associated diseases. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Mouse RAGE / AGER protein (TMPY-01675) |
| Antigen Species | Mouse |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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