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Myosin H Chain Fragment, Mouse
🥰Excellent
Catalog No. T78375
Myosin H Chain Fragment, Mouse is a peptide fragment derived from the α-myosin heavy chain that serves as a critical immunogenic determinant used to induce experimental autoimmune myocarditis (EAM) in murine models. Myosin H Chain Fragment, Mouse is applied in cardiovascular immunopathology research to elucidate the mechanisms underlying autoimmune-mediated cardiac inflammation and subsequent myocardial injury.
Myosin H Chain Fragment, Mouse
Myosin H Chain Fragment, Mouse
🥰Excellent
Purity: 99.204%
Catalog No. T78375
Myosin H Chain Fragment, Mouse is a peptide fragment derived from the α-myosin heavy chain that serves as a critical immunogenic determinant used to induce experimental autoimmune myocarditis (EAM) in murine models. Myosin H Chain Fragment, Mouse is applied in cardiovascular immunopathology research to elucidate the mechanisms underlying autoimmune-mediated cardiac inflammation and subsequent myocardial injury.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $61 | In Stock | |
| 5 mg | $147 | In Stock | |
| 10 mg | $247 | In Stock | |
| 25 mg | $538 | In Stock | |
| 50 mg | $766 | In Stock |
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Purity:99.204%
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Product Introduction
Bioactivity
Chemical Properties
| Description | Myosin H Chain Fragment, Mouse is a peptide fragment derived from the α-myosin heavy chain that serves as a critical immunogenic determinant used to induce experimental autoimmune myocarditis (EAM) in murine models. Myosin H Chain Fragment, Mouse is applied in cardiovascular immunopathology research to elucidate the mechanisms underlying autoimmune-mediated cardiac inflammation and subsequent myocardial injury. |
| In vivo | Myosin H Chain Fragment, Mouse (150 μg) was emulsified with PBS/CFA (1 mg/mL, H37Ra) at a 1:1 ratio and then subcutaneously injected into mice, with two injections administered 7 days apart (on day 0 and day 7, respectively), which can induce experimental autoimmune myocarditis. [1] |
| Molecular Weight | 2073.37 |
| Formula | C91H149N25O28S |
| Color | White |
| Appearance | Solid |
| Sequence | Ac-Arg-Ser-Leu-Lys-Leu-Met-Ala-Thr-Leu-Phe-Ser-Thr-Tyr-Ala-Ser-Ala-Asp-Arg |
| Sequence Short | Ac-RSLKLMATLFSTYASADR |
Storage & Solubility Information
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | ||||||||||||||||||||
| Solubility Information | H2O: 12 mg/mL (5.79 mM), Sonication is recommended. DMSO: 9.5 mg/mL (4.58 mM), Sonication is recommended. | ||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||
DMSO/H2O
H2O
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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