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GSK2838232

Name: GSK2838232
Brand: TargetMol
SKU: T15436
Price: 64 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T15436Cas No. 1443460-91-0

GSK2838232, a novel human immunodeficiency virus (HIV) maturation inhibitor, inhibits HIV reverse transcriptase activity across a broad panel of HIV-1 isolates.

GSK2838232

🥰Excellent

Purity: 97.97%

Catalog No. T15436Cas No. 1443460-91-0

GSK2838232, a novel human immunodeficiency virus (HIV) maturation inhibitor, inhibits HIV reverse transcriptase activity across a broad panel of HIV-1 isolates.

Pack Size	Price	Availability
1 mg	$64	In Stock
5 mg	$139	In Stock
10 mg	$222	In Stock
25 mg	$488	In Stock
50 mg	$712	In Stock
100 mg	$987	In Stock
1 mL x 10 mM (in DMSO)	$197	In Stock

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Batch Information

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Purity:97.97%

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COA HNMR LCMS

Product Introduction

Bioactivity

Description

GSK2838232, a novel human immunodeficiency virus (HIV) maturation inhibitor, inhibits HIV reverse transcriptase activity across a broad panel of HIV-1 isolates.

Chemical Properties

Molecular Weight	809.56
Formula	C₄₈H₇₃ClN₂O₆
Cas No.	1443460-91-0
Smiles	[H][C@]12CC[C@]3([H])[C@@]4(C)CC[C@H](OC(=O)CC(C)(C)C(O)=O)C(C)(C)[C@]4([H])CC[C@@]3(C)[C@]1(C)CC[C@]1(CC(=O)C(C(C)C)=C21)[C@@H](O)CN(CCN(C)C)Cc1ccc(Cl)cc1
Relative Density.	1.17 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (61.76 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.2352 mL	6.1762 mL	12.3524 mL	61.7619 mL
5 mM	0.2470 mL	1.2352 mL	2.4705 mL	12.3524 mL
10 mM	0.1235 mL	0.6176 mL	1.2352 mL	6.1762 mL
20 mM	0.0618 mL	0.3088 mL	0.6176 mL	3.0881 mL
50 mM	0.0247 mL	0.1235 mL	0.2470 mL	1.2352 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc