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Mauritianin

Name: Mauritianin
Brand: TargetMol
SKU: TN1917
Price: 85 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. TN1917Cas No. 109008-28-8

Mauritianin, a kaempferol glycoside isolated from the flowers and leaves of Acalypha indica, is a topoisomerase I inhibitor with cytoprotective activity.

Mauritianin

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Purity: 97.5%

Catalog No. TN1917Cas No. 109008-28-8

Mauritianin, a kaempferol glycoside isolated from the flowers and leaves of Acalypha indica, is a topoisomerase I inhibitor with cytoprotective activity.

Pack Size	Price	Availability
1 mg	$85	In Stock
5 mg	$249	In Stock
10 mg	$438	In Stock
25 mg	$696	In Stock

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Purity:97.5%

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COA HPLC HNMR

Product Introduction

Bioactivity

Description	Mauritianin, a kaempferol glycoside isolated from the flowers and leaves of Acalypha indica, is a topoisomerase I inhibitor with cytoprotective activity.
In vitro	Bioassay-guided fractionation resulted in the isolation of Mauritianin as a new topoisomerase I inhibitor.[1] After 14 weeks, Mauritianin antagonized the flavonol glycosides on cell-mediated immunosuppression in the two-stage carcinogenesis in terms of initiation.[3]

Chemical Properties

Molecular Weight	740.66
Formula	C₃₃H₄₀O₁₉
Cas No.	109008-28-8
Smiles	[H][C@@]1(O[C@H]2[C@H](Oc3c(oc4cc(O)cc(O)c4c3=O)-c3ccc(O)cc3)O[C@H](CO[C@@H]3O[C@@H](C)[C@H](O)[C@@H](O)[C@H]3O)[C@H](O)[C@@H]2O)O[C@@H](C)[C@H](O)[C@@H](O)[C@H]1O
Relative Density.	1.74g/cm3

Storage & Solubility Information

Storage

store at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 90.0 mg/mL (121.5 mM ), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.3501 mL	6.7507 mL	13.5015 mL	67.5074 mL
5 mM	0.2700 mL	1.3501 mL	2.7003 mL	13.5015 mL
10 mM	0.1350 mL	0.6751 mL	1.3501 mL	6.7507 mL
20 mM	0.0675 mL	0.3375 mL	0.6751 mL	3.3754 mL
50 mM	0.0270 mL	0.1350 mL	0.2700 mL	1.3501 mL
100 mM	0.0135 mL	0.0675 mL	0.1350 mL	0.6751 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc