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Mauritianin

Name: Mauritianin
Brand: TargetMol
SKU: TN1917
Price: 85 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. TN1917Cas No. 109008-28-8

Mauritianin, a kaempferol glycoside isolated from the flowers and leaves of Acalypha indica, is a topoisomerase I inhibitor with cytoprotective activity.

Mauritianin

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Purity: 97.5%

Catalog No. TN1917Cas No. 109008-28-8

Mauritianin, a kaempferol glycoside isolated from the flowers and leaves of Acalypha indica, is a topoisomerase I inhibitor with cytoprotective activity.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$85	-	In Stock
5 mg	$249	-	In Stock
10 mg	$438	-	In Stock
25 mg	$696	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:97.5%

Appearance:Solid

Color:Yellow

Resource Download

COA HPLC HNMR

Product Introduction

Bioactivity

Description	Mauritianin, a kaempferol glycoside isolated from the flowers and leaves of Acalypha indica, is a topoisomerase I inhibitor with cytoprotective activity.
In vitro	Bioassay-guided fractionation resulted in the isolation of Mauritianin as a new topoisomerase I inhibitor.[1] After 14 weeks, Mauritianin antagonized the flavonol glycosides on cell-mediated immunosuppression in the two-stage carcinogenesis in terms of initiation.[3]

Chemical Properties

Molecular Weight	740.66
Formula	C₃₃H₄₀O₁₉
Cas No.	109008-28-8
Smiles	[H][C@@]1(O[C@H]2[C@H](Oc3c(oc4cc(O)cc(O)c4c3=O)-c3ccc(O)cc3)O[C@H](CO[C@@H]3O[C@@H](C)[C@H](O)[C@@H](O)[C@H]3O)[C@H](O)[C@@H]2O)O[C@@H](C)[C@H](O)[C@@H](O)[C@H]1O
Relative Density.	1.74g/cm3

Storage & Solubility Information

Storage

store at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 90 mg/mL (121.51 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 3.3 mg/mL (4.46 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.3501 mL	6.7507 mL	13.5015 mL	67.5074 mL
5 mM	0.2700 mL	1.3501 mL	2.7003 mL	13.5015 mL
10 mM	0.1350 mL	0.6751 mL	1.3501 mL	6.7507 mL
20 mM	0.0675 mL	0.3375 mL	0.6751 mL	3.3754 mL
50 mM	0.0270 mL	0.1350 mL	0.2700 mL	1.3501 mL
100 mM	0.0135 mL	0.0675 mL	0.1350 mL	0.6751 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc