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Hainantoxin-III

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Catalog No. T80186Cas No. 1809149-40-3

Jingzhaotoxin-V is a peptide that suppresses potassium currents in Xenopus laevis oocytes with an IC50 of 604.2 nM, while targeting both tetrodotoxin-resistant and tetrodotoxin-sensitive sodium currents in rat dorsal root ganglion neurons with IC50 values of 27.6 nM and 30.2 nM, respectively [1].

Hainantoxin-III

Hainantoxin-III

😃Good
Catalog No. T80186Cas No. 1809149-40-3
Jingzhaotoxin-V is a peptide that suppresses potassium currents in Xenopus laevis oocytes with an IC50 of 604.2 nM, while targeting both tetrodotoxin-resistant and tetrodotoxin-sensitive sodium currents in rat dorsal root ganglion neurons with IC50 values of 27.6 nM and 30.2 nM, respectively [1].
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Jingzhaotoxin-V is a peptide that suppresses potassium currents in Xenopus laevis oocytes with an IC50 of 604.2 nM, while targeting both tetrodotoxin-resistant and tetrodotoxin-sensitive sodium currents in rat dorsal root ganglion neurons with IC50 values of 27.6 nM and 30.2 nM, respectively [1].
Chemical Properties
Molecular Weight3608.12
FormulaC154H228N44O45S6
Cas No.1809149-40-3
SmilesC(C=1C=2C(NC1)=CC=CC2)[C@H]3C(=O)N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC4=CC=C(O)C=C4)C(N[C@@H](CC(C)C)C(N)=O)=O)=O)[C@@H](C)C)=O)CCCCN)=O)CSSC[C@]5(C(=O)N[C@@]6(C(=O)N7[C@](C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC8=CC=C(O)C=C8)C(=O)N[C@@H](C)C(=O)N[C@](C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC9=CN=CN9)C(=O)N[C@@H](CCCCN)C(=O)N3)(CSSCC(C(=O)N[C@@]([C@@H](C)O)(C(=O)N%10[C@](C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N5)(CCC%10)[H])[H])(NC(=O)[C@H](CO)NC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@H](CC%11=CC=CC=C%11)NC(=O)CNC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(CN)=O)CSSC6)[H])[H])(CCC7)[H])[H])[H]
SequenceGly-Cys-Lys-Gly-Phe-Gly-Asp-Ser-Cys-Thr-Pro-Gly-Lys-Asn-Glu-Cys-Cys-Pro-Asn-Tyr-Ala-Cys-Ser-Ser-Lys-His-Lys-Trp-Cys-Lys-Val-Tyr-Leu-NH2 (Disulfide bonds: Cys2-Cys17, Cys9-Cys22, Cys16-Cys29)
Sequence ShortGCKGFGDSCTPGKNECCPNYACSSKHKWCKVYL-NH2 (Disulfide bonds: Cys2-Cys17, Cys9-Cys22, Cys16-Cys29)
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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Keywords

SodiumChannelSodium Channel
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