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Lebrikizumab (Synonyms: TNX-650, TNX650, RO5490255, RO 5490255, RG 3637, LY 3650150)

Catalog No. T76686 Copy Product Info
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Lebrikizumab is a humanised monoclonal antibody that targets and inhibits interleukin 13 (IL-13), thereby suppressing Th2 inflammation. It is mainly used in the study of asthma and atopic dermatitis.

Lebrikizumab

Copy Product Info
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Catalog No. T76686
Synonyms TNX-650, TNX650, RO5490255, RO 5490255, RG 3637, LY 3650150

Lebrikizumab is a humanised monoclonal antibody that targets and inhibits interleukin 13 (IL-13), thereby suppressing Th2 inflammation. It is mainly used in the study of asthma and atopic dermatitis.

Lebrikizumab
Cas No. 953400-68-5
Pack SizePriceUSA StockGlobal StockQuantity
1 mg$215-In Stock
5 mg$560-In Stock
10 mg$896-In Stock
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Batch Information

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Purity:96.3% (SDS-PAGE); 96.2% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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Product Introduction

Bioactivity
Description
Lebrikizumab is a humanised monoclonal antibody that targets and inhibits interleukin 13 (IL-13), thereby suppressing Th2 inflammation. It is mainly used in the study of asthma and atopic dermatitis.
In vitro
Lebrikizumab (500 μg/mL, 1 mg/mL, 24 hours) effectively inhibited IL-13-induced neurosensitization responses to each of the three pruritic substances in vitro.[1]
SynonymsTNX-650, TNX650, RO5490255, RO 5490255, RG 3637, LY 3650150
Reactivity
Human
Application
Functional assay
Antibody Type
Monoclonal
FormulationSupplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Gene ID
Uniprot ID
TargetIL-13
Chemical Properties
Molecular Weight145.27 kDa
Cas No.953400-68-5
Antibody Information
IsotypeHuman IgG4 kappa
Recommended Isotype Control
Storage & Solubility Information
Storagestore at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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