keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ac2-12 TFA, an annexin/lipocortin 1 (LC1)-mimetic peptide, inhibits neutrophil extravasation and demonstrates antimigratory effects by attenuating the recruitment of neutrophils in experimental models of inflammation [1] [2].
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50 mg | Inquiry | Inquiry |
Description | Ac2-12 TFA, an annexin/lipocortin 1 (LC1)-mimetic peptide, inhibits neutrophil extravasation and demonstrates antimigratory effects by attenuating the recruitment of neutrophils in experimental models of inflammation [1] [2]. |
In vivo | Ac2-12 TFA, administered intravenously at a dosage of 6.7 mg/kg (approximately 70 nmol per mouse), emulates the effects of lipocortin 1 (LC1) and Ac2-26 in male Swiss Albino mice weighing 10-15 grams [1]. Furthermore, a 100 μg dose notably diminishes polymorphonuclear leukocyte (PMN) infiltration in C57BL/6 wild-type mice, while it lacks efficacy in FPR knockout (KO) mice [2]. |
Molecular Weight | N/A |
keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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