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TA-02

Name: TA-02
Brand: TargetMol
SKU: T4646
Price: 256 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T4646Cas No. 1784751-19-4

TA-02 is a p38 MAPK inhibitor with IC50 of 20 nM.TA-02 especially inhibits TGFBR-2.

TA-02

🥰Excellent

Purity: 99.79%

Catalog No. T4646Cas No. 1784751-19-4

TA-02 is a p38 MAPK inhibitor with IC50 of 20 nM.TA-02 especially inhibits TGFBR-2.

Pack Size	Price	Availability
5 mg	$33	In Stock
10 mg	$53	In Stock
25 mg	$106	In Stock
50 mg	$163	In Stock
100 mg	$256	In Stock
500 mg	Preferential	In Stock
1 mL x 10 mM (in DMSO)	$36	In Stock

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Batch Information

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Purity:99.79%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	TA-02 is a p38 MAPK inhibitor with IC50 of 20 nM.TA-02 especially inhibits TGFBR-2.
Targets&IC50	p38 MAPK:20 nM

Chemical Properties

Molecular Weight	333.33
Formula	C₂₀H₁₃F₂N₃
Cas No.	1784751-19-4
Smiles	Fc1ccc(cc1)-c1nc([nH]c1-c1ccncc1)-c1ccccc1F
Relative Density.	1.289 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (150 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.0000 mL	15.0002 mL	30.0003 mL	150.0015 mL
5 mM	0.6000 mL	3.0000 mL	6.0001 mL	30.0003 mL
10 mM	0.3000 mL	1.5000 mL	3.0000 mL	15.0002 mL
20 mM	0.1500 mL	0.7500 mL	1.5000 mL	7.5001 mL
50 mM	0.0600 mL	0.3000 mL	0.6000 mL	3.0000 mL
100 mM	0.0300 mL	0.1500 mL	0.3000 mL	1.5000 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc