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Advantame

Name: Advantame
Brand: TargetMol
SKU: T83161
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T83161Cas No. 714229-20-6

Advantame is an N-alkylation derivative of aspartic acid of aspartyl sweetener, and is also a low-calorie sweetener with good tolerance in animals and humans.

Advantame

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Purity: 99.10%

Catalog No. T83161Cas No. 714229-20-6

Advantame is an N-alkylation derivative of aspartic acid of aspartyl sweetener, and is also a low-calorie sweetener with good tolerance in animals and humans.

Pack Size	Price	USA Warehouse	Global Warehouse
25 mg	$44	-	In Stock
50 mg	$60	-	In Stock
100 mg	$77	-	In Stock
1 mL x 10 mM (in DMSO)	$29	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.10%

Appearance:Solid

Color:White

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description

Advantame is an N-alkylation derivative of aspartic acid of aspartyl sweetener, and is also a low-calorie sweetener with good tolerance in animals and humans.

Chemical Properties

Molecular Weight	476.52
Formula	C₂₄H₃₂N₂O₈
Cas No.	714229-20-6
Smiles	[C@@H](CC1=CC=CC=C1)(NC([C@@H](NCCCC2=CC(O)=C(OC)C=C2)CC(O)=O)=O)C(OC)=O.O

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 80 mg/mL (167.88 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.0985 mL	10.4927 mL	20.9855 mL	104.9274 mL
5 mM	0.4197 mL	2.0985 mL	4.1971 mL	20.9855 mL
10 mM	0.2099 mL	1.0493 mL	2.0985 mL	10.4927 mL
20 mM	0.1049 mL	0.5246 mL	1.0493 mL	5.2464 mL
50 mM	0.0420 mL	0.2099 mL	0.4197 mL	2.0985 mL
100 mM	0.0210 mL	0.1049 mL	0.2099 mL	1.0493 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc