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XM462 is a dihydroceramide desaturase inhibitor that exhibits mixed-type inhibition (K i = 2 μM) in vitro. It demonstrates dihydroceramide desaturase inhibition in both in vitro and cultured cells, with IC 50 values of 8.2 μM and 0.78 μM, respectively. XM462 is applicable for tumor research [1] [2].

| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 10 mg | Inquiry | 10-14 weeks | 10-14 weeks | |
| 50 mg | Inquiry | 10-14 weeks | 10-14 weeks |
| Description | XM462 is a dihydroceramide desaturase inhibitor that exhibits mixed-type inhibition (K i = 2 μM) in vitro. It demonstrates dihydroceramide desaturase inhibition in both in vitro and cultured cells, with IC 50 values of 8.2 μM and 0.78 μM, respectively. XM462 is applicable for tumor research [1] [2]. |
| Molecular Weight | 445.74 |
| Formula | C25H51NO3S |
| Cas No. | 1045857-53-1 |
| Smiles | [C@@H](NC(CCCCCCC)=O)([C@@H](CSCCCCCCCCCCCCC)O)CO |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Dissolve 2 mg of the compound in 100 μL DMSO
to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO
stock solution to 400 μL PEG300
and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O
and mix thoroughly until a homogeneous solution is obtained.
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