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α-2,3-sialyltransferase-IN-1

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Catalog No. T13429Cas No. 881179-06-2
Alias Lith-O-Asp analog

α-2,3-sialyltransferase-IN-1 (Lith-O-Asp analog) is an α-2,3-sialyltransferase inhibitor with anticancer activity. Vapendavir diphosphate inhibits EV71 replication.

α-2,3-sialyltransferase-IN-1

α-2,3-sialyltransferase-IN-1

😃Good
Purity: 98%
Catalog No. T13429Alias Lith-O-Asp analogCas No. 881179-06-2
α-2,3-sialyltransferase-IN-1 (Lith-O-Asp analog) is an α-2,3-sialyltransferase inhibitor with anticancer activity. Vapendavir diphosphate inhibits EV71 replication.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 mg$1,5206-8 weeks6-8 weeks
50 mg$1,9806-8 weeks6-8 weeks
100 mg$2,5006-8 weeks6-8 weeks
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Expected start date of shipmentUSA Warehouse [1-2 days] Global Warehouse [5-7 days]
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Purity:98%
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Product Introduction

Bioactivity
Description
α-2,3-sialyltransferase-IN-1 (Lith-O-Asp analog) is an α-2,3-sialyltransferase inhibitor with anticancer activity. Vapendavir diphosphate inhibits EV71 replication.
Targets&IC50
α-2,3-sialyltransferase:6 μM
In vitro
α-2,3-sialyltransferase-IN-1 is a non-competitive inhibitor of α-2,3-sialyltransferase with an IC50 value of 6 μM. α-2,3-sialyltransferase-IN-1 is compound 17 in the reference. [1]
SynonymsLith-O-Asp analog
Chemical Properties
Molecular Weight491.66
FormulaC28H45NO6
Cas No.881179-06-2
SmilesC[C@@]12[C@]([C@]3([C@@]([C@]4(C)[C@](CC3)(C[C@H](OC([C@@H](CC(O)=O)N)=O)CC4)[H])(CC1)[H])[H])(CC[C@@]2([C@@H](CCC(O)=O)C)[H])[H]
Relative Density.1.19 g/cm3 (Predicted)
ColorTransparent
AppearanceLiquid
Storage & Solubility Information
Storagestore at low temperature | Pure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 80 mg/mL (162.71 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.0339 mL10.1696 mL20.3393 mL101.6963 mL
5 mM0.4068 mL2.0339 mL4.0679 mL20.3393 mL
10 mM0.2034 mL1.0170 mL2.0339 mL10.1696 mL
20 mM0.1017 mL0.5085 mL1.0170 mL5.0848 mL
50 mM0.0407 mL0.2034 mL0.4068 mL2.0339 mL
100 mM0.0203 mL0.1017 mL0.2034 mL1.0170 mL

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Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Keywords

α-2,3-sialyltransferase-IN-1α2,3sialyltransferaseIN1α-2,3-sialyltransferaseα 2,3 sialyltransferase IN 1Sialyltransferasealpha-2,3-sialyltransferase-IN-1a-2,3-sialyltransferase-IN-1
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