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Lutikizumab
(Synonyms: ABT-981) Copy Product Info
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Synonyms: ABT-981
Catalog No. T77077 Copy Product Info
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Lutikizumab is a bispecific antibody against IL-1α and IL-1β with a bivalent variable domain structure. By binding to IL-1α and IL-1β, Lutikizumab effectively inhibits their activity and is mainly used in the field of osteoarthritis research.
Cas No. 1791411-57-8
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $456 | - | In Stock | |
| 5 mg | $1,160 | - | In Stock | |
| 10 mg | $1,850 | - | In Stock |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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With extensive experience in compound synthesis, we can provide rapid custom synthesis services for this product according to your research needs.
For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:>95% (SDS-PAGE); 99.63% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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Related Conjugates and Formulations
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| Description | Lutikizumab is a bispecific antibody against IL-1α and IL-1β with a bivalent variable domain structure. By binding to IL-1α and IL-1β, Lutikizumab effectively inhibits their activity and is mainly used in the field of osteoarthritis research. |
| In vitro | Lutikizumab binds specifically to both human IL‑1α and IL‑1β proteins.Compared with other cytokines in the IL‑1 family, lutikizumab exhibits highly specific binding to both IL‑1α and IL‑1β [1]. |
| In vivo | Lutikizumab significantly inhibits IL‑6 production induced by IL‑1α and IL‑1β following a single intraperitoneal injection at doses of 0.0001–1 mg/kg [1]. |
| Synonyms | ABT-981 |
| Reactivity | Human |
| Application | Functional assay |
| Antibody Type | Monoclonal, Bispecific |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | IL-1α/IL-1β |
| Molecular Weight | 196.82 kDa |
| Cas No. | 1791411-57-8 |
| Isotype | Human IgG1 kappa |
| Recommended Isotype Control |
| Storage | Store at low temperature Store at -20°C Shipping with blue ice/Shipping at ambient temperature. |
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Related Tags: Lutikizumab chemical structure | Lutikizumab in vivo | Lutikizumab in vitro | Lutikizumab molecular weight
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