Powder: -20°C for 3 years | In solvent: -80°C for 1 year
MI-1061 TFA, a potent and orally bioavailable MDM2 inhibitor (MDM2-p53 interaction), demonstrates significant chemical stability with an IC 50 of 4.4 nM and a K i of 0.16 nM. It effectively activates p53 and induces apoptosis within SJSA-1 xenograft tumor tissues in mice, showcasing notable anti-tumor activity [1].
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Description | MI-1061 TFA, a potent and orally bioavailable MDM2 inhibitor (MDM2-p53 interaction), demonstrates significant chemical stability with an IC 50 of 4.4 nM and a K i of 0.16 nM. It effectively activates p53 and induces apoptosis within SJSA-1 xenograft tumor tissues in mice, showcasing notable anti-tumor activity [1]. |
Molecular Weight | 696.47 |
Formula | C32H27Cl2F4N3O6 |
CAS No. | 1410737-35-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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MI-1061 TFA 1410737-35-7 inhibitor inhibit