Powder: -20°C for 3 years | In solvent: -80°C for 1 year
QR-0217 is a potent inhibitor of both Aβ1-40 and α-synuclein aggregation, exhibiting an IC50 of 7.5 µM for Aβ1-40. Additionally, QR-0217 has been shown to alleviate memory impairments attributed to Aβ neurotoxicity [1].
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50 mg | Inquiry | Inquiry |
Description | QR-0217 is a potent inhibitor of both Aβ1-40 and α-synuclein aggregation, exhibiting an IC50 of 7.5 µM for Aβ1-40. Additionally, QR-0217 has been shown to alleviate memory impairments attributed to Aβ neurotoxicity [1]. |
In vitro | QR-0217 at concentrations of 20 and 100 µM after 96 hours suppresses the aggregation of α-synuclein at a concentration of 4 μM [1]. Additionally, at a concentration of 50 µM, QR-0217 significantly rescues the impairment of long-term potentiation (LTP) in hippocampal slices from APP/PS1 transgenic mice [1]. |
Molecular Weight | 303.31 |
Formula | C19H13NO3 |
CAS No. | 1027786-12-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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QR-0217 1027786-12-4 inhibitor inhibit