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Anti-KDM1B Antibody (3U825) is an antibody targeting KDM1B. Anti-KDM1B Antibody (3U825) can be used in ELISA, WB.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $209 | 7-10 days | |
100 μL | $347 | 7-10 days |
Description | Antibody Type: Recombinant Monoclonal Application: ELISA, WB Reactivity: Human |
Alias | Lysine-specific histone demethylase 2, Lysine-specific histone demethylase 1B, LSD2, Flavin-containing amine oxidase domain-containing protein 1, C6orf193, AOF1 |
Ig Type | Rabbit IgG |
Clone | 3U825 |
Reactivity | Human |
Verified Activity | Western Blot -Positive WB detected in: A549 whole cell lysate, Hela whole cell lysate -All lanes: KDM1B antibody at 1:2000 -Secondary: Goat polyclonal to rabbit IgG at 1/50000 dilution -Predicted band size: 93, 66, 20 kDa -Observed band size: 90-95, 17-28 kDa |
Application | ELISA, WB |
Recommended Dose | WB:1:500-1:2000. |
Antibody Type | Monoclonal |
Subcellular Localization | Nucleus. |
Construction | Recombinant Antibody |
Purification | Affinity-chromatography |
Appearance | Liquid |
Formulation | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Research Background | Histone demethylase that demethylates 'Lys-4' of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. Required for de novo DNA methylation of a subset of imprinted genes during oogenesis. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Demethylates both mono- and di-methylated 'Lys-4' of histone H3. Has no effect on tri-methylated 'Lys-4', mono-, di- or tri-methylated 'Lys-9', mono-, di- or tri-methylated 'Lys-27', mono-, di- or tri-methylated 'Lys-36' of histone H3, or on mono-, di- or tri-methylated 'Lys-20' of histone H4. |
Conjucates | Unconjugated |
Immunogen | A synthetic peptide: Human KDM1B |
Antigen Species | Human |
Gene ID | 221656 |
Uniprot ID | |
Biology Area | Epigenetics and Nuclear Signaling |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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