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Anti-KDM1B Antibody (3U825)

😃Good
Catalog No. TMAH-00663
Alias Lysine-specific histone demethylase 2, Lysine-specific histone demethylase 1B, LSD2, Flavin-containing amine oxidase domain-containing protein 1, C6orf193, AOF1

Anti-KDM1B Antibody (3U825) is an antibody targeting KDM1B. Anti-KDM1B Antibody (3U825) can be used in ELISA, WB.

Anti-KDM1B Antibody (3U825)

Anti-KDM1B Antibody (3U825)

😃Good
Catalog No. TMAH-00663Alias Lysine-specific histone demethylase 2, Lysine-specific histone demethylase 1B, LSD2, Flavin-containing amine oxidase domain-containing protein 1, C6orf193, AOF1
Anti-KDM1B Antibody (3U825) is an antibody targeting KDM1B. Anti-KDM1B Antibody (3U825) can be used in ELISA, WB.
Pack SizePriceAvailabilityQuantity
50 μL$209 7-10 days
100 μL$347 7-10 days
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Product Introduction

Bioactivity
Description
Antibody Type: Recombinant Monoclonal

Application: ELISA, WB

Reactivity: Human
AliasLysine-specific histone demethylase 2, Lysine-specific histone demethylase 1B, LSD2, Flavin-containing amine oxidase domain-containing protein 1, C6orf193, AOF1
Ig Type
Rabbit IgG
Clone
3U825
Reactivity
Human
Verified Activity
Western Blot
-Positive WB detected in: A549 whole cell lysate, Hela whole cell lysate
-All lanes: KDM1B antibody at 1:2000
-Secondary: Goat polyclonal to rabbit IgG at 1/50000 dilution
-Predicted band size: 93, 66, 20 kDa
-Observed band size: 90-95, 17-28 kDa
Application
ELISA, WB
Recommended Dose
WB:1:500-1:2000.
Antibody Type
Monoclonal
Subcellular LocalizationNucleus.
ConstructionRecombinant Antibody
PurificationAffinity-chromatography
AppearanceLiquid
FormulationPhosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Research BackgroundHistone demethylase that demethylates 'Lys-4' of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. Required for de novo DNA methylation of a subset of imprinted genes during oogenesis. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Demethylates both mono- and di-methylated 'Lys-4' of histone H3. Has no effect on tri-methylated 'Lys-4', mono-, di- or tri-methylated 'Lys-9', mono-, di- or tri-methylated 'Lys-27', mono-, di- or tri-methylated 'Lys-36' of histone H3, or on mono-, di- or tri-methylated 'Lys-20' of histone H4.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
A synthetic peptide: Human KDM1B
Antigen Species
Human
Gene ID
221656
Uniprot ID
Biology Area
Epigenetics and Nuclear Signaling
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

Sci Citations

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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