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Anti-GBA Antibody (7E768)
Catalog No. TMAH-00476 Copy Product Info
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Anti-GBA Antibody (7E768) is an antibody targeting GBA. Anti-GBA Antibody (7E768) can be used in ELISA,WB.
Anti-GBA Antibody (7E768)
Copy Product Info🥰Excellent
Catalog No. TMAH-00476
Anti-GBA Antibody (7E768) is an antibody targeting GBA. Anti-GBA Antibody (7E768) can be used in ELISA,WB.
Anti-GBA Antibody
(7E768)
(7E768)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $209 | 7-10 days | 7-10 days | |
| 100 μL | $349 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-GBA Antibody (7E768) is an antibody targeting GBA. Anti-GBA Antibody (7E768) can be used in ELISA,WB. |
| Ig Type | Rabbit IgG |
| Clone | 7E768 |
| Reactivity | Human |
| Verified Activity | Western Blot -Positive WB detected in: Hela whole cell lysate, MCF-7 whole cell lysate, 293T whole cell lysate, U87 whole cell lysate -All lanes: GBA antibody at 1:2000 -Secondary: Goat polyclonal to rabbit IgG at 1/50000 dilution -Predicted band size: 60, 58, 55, 51, 30 kDa -Observed band size: 60 kDa |
| Application | |
| Recommended Dose | WB:1:500-1:5000. |
| Antibody Type | Monoclonal |
| Subcellular Localization | Lysosome membrane; Peripheral membrane protein; Lumenal side. |
| Construction | Recombinant Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Glucosylceramidase that catalyzes, within the lysosomal compartment, the hydrolysis of glucosylceramide/GlcCer into free ceramide and glucose. Thereby, plays a central role in the degradation of complex lipids and the turnover of cellular membranes. Through the production of ceramides, participates in the PKC-activated salvage pathway of ceramide formation. Also plays a role in cholesterol metabolism. May either catalyze the glucosylation of cholesterol, through a transglucosylation reaction that transfers glucose from glucosylceramide to cholesterol. The short chain saturated C8:0-GlcCer and the mono-unsaturated C18:0-GlcCer being the most effective glucose donors for that transglucosylation reaction. Under specific conditions, may alternatively catalyze the reverse reaction, transferring glucose from cholesteryl-beta-D-glucoside to ceramide. Finally, may also hydrolyze cholesteryl-beta-D-glucoside to produce D-glucose and cholesterol. |
| Conjucates | Unconjugated |
| Immunogen | A synthetic peptide: Human GBA |
| Antigen Species | Human |
| Gene Name | GBA |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Neuroscience, Cancer, Metabolism, Signal transduction |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Keywords
β-glucosylceramidase 1β-glucocerebrosidase (β-GC)β-GCβGCSGTaseLysosomal glycosylceramidaseLysosomal galactosylceramidaseLysosomal cholesterol glycosyltransferaseLysosomal acid glucosylceramidaseLysosomal acid GCaseImigluceraseGlucosylceramidase β 1Glucosylceramidase beta 1Glucosylceramidase b 1GLUCGCGBA1GBA 1GBAD-glucosyl-N-acylsphingosine glucohydrolaseCholesteryl-β-glucosidaseCholesteryl-b-glucosidaseCholesteryl-beta-glucosidaseCholesterol glucosyltransferase (SGTase)b-glucosylceramidase 1b-glucocerebrosidase (b-GC)b-GCbGCBeta-glucosylceramidase 1Beta-glucocerebrosidase (Beta-GC)Beta-GCBetaGCAlgluceraseAcid β-glucosidaseAcid b-glucosidaseAcid beta-glucosidase
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