Anti-GBA Antibody (7E768)

Name: Anti-GBA Antibody (7E768)
Brand: TargetMol
SKU: TMAH-00476
Rating: 4.5 (1 reviews)

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Catalog No. TMAH-00476

Anti-GBA Antibody (7E768) is an antibody targeting GBA. Anti-GBA Antibody (7E768) can be used in ELISA, WB.

Anti-GBA Antibody (7E768)

😃Good

Catalog No. TMAH-00476

Anti-GBA Antibody (7E768) is an antibody targeting GBA. Anti-GBA Antibody (7E768) can be used in ELISA, WB.

Pack Size	Price	Availability	Quantity
50 μL	$209	7-10 days
100 μL	$349	7-10 days

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Instruction Manual of Detection Antibody

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Product Introduction

Bioactivity

Description	Antibody Type: Recombinant Rabbit Monoclonal Application: ELISA, WB Reactivity: Human
Ig Type	Rabbit IgG
Clone	7E768
Reactivity	Human
Verified Activity	Western Blot -Positive WB detected in: Hela whole cell lysate, MCF-7 whole cell lysate, 293T whole cell lysate, U87 whole cell lysate -All lanes: GBA antibody at 1:2000 -Secondary: Goat polyclonal to rabbit IgG at 1/50000 dilution -Predicted band size: 60, 58, 55, 51, 30 kDa -Observed band size: 60 kDa
Application	ELISA, WB
Recommended Dose	WB:1:500-1:5000.
Antibody Type	Monoclonal
Subcellular Localization	Lysosome membrane; Peripheral membrane protein; Lumenal side.
Construction	Recombinant Antibody
Purification	Affinity-chromatography
Appearance	Liquid
Formulation	Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Research Background	Glucosylceramidase that catalyzes, within the lysosomal compartment, the hydrolysis of glucosylceramide/GlcCer into free ceramide and glucose. Thereby, plays a central role in the degradation of complex lipids and the turnover of cellular membranes. Through the production of ceramides, participates in the PKC-activated salvage pathway of ceramide formation. Also plays a role in cholesterol metabolism. May either catalyze the glucosylation of cholesterol, through a transglucosylation reaction that transfers glucose from glucosylceramide to cholesterol. The short chain saturated C8:0-GlcCer and the mono-unsaturated C18:0-GlcCer being the most effective glucose donors for that transglucosylation reaction. Under specific conditions, may alternatively catalyze the reverse reaction, transferring glucose from cholesteryl-beta-D-glucoside to ceramide. Finally, may also hydrolyze cholesteryl-beta-D-glucoside to produce D-glucose and cholesterol.

Related Conjugates and Formulations

Conjucates

Unconjugated

Antigen Details

Immunogen	A synthetic peptide: Human GBA
Antigen Species	Human
Gene ID	2629
Uniprot ID	P04062
Biology Area	Neuroscience, Cancer, Metabolism, Signal transduction

Chemical Properties

Stability & Storage

Stability & Storage	Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
Transport	Shipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc