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Antioxidant agent-11

Name: Antioxidant agent-11
Brand: TargetMol
SKU: T83030
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

Catalog No. T83030 Copy Product Info

Purity: 99.55%

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Antioxidant agent-11 (Compound 3d) is a novel 2,3-dihydroquinazolin-4(1H)-ones derivative exhibiting preliminary anticancer and antioxidant activities. As a synthetic small molecule, it is utilized to evaluate the impact of specific aryl and pyrazole substituents on the biological activity of the dihydroquinazolinone scaffold. Research indicates that the compound shows moderate efficacy in free radical scavenging and cancer cell proliferation inhibition, serving as a reference for structure-activity relationship (SAR) studies of this scaffold.

Antioxidant agent-11

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Catalog No. T83030

Cas No. 474379-42-5

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Pack Size	Price	USA Stock	Global Stock
2 mg	$30	-	In Stock
5 mg	$48	-	In Stock
10 mg	$73	-	In Stock
25 mg	$118	-	In Stock
50 mg	$176	-	In Stock

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:99.55%

Appearance:Solid

Color:White

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COA HNMR LCMS

Product Introduction

Bioactivity

Description

In vitro

Antioxidant agent-11 exhibits weak anticancer and antioxidant activities; its biological potency is influenced by the 2-position substituents [1].

Chemical Properties

Molecular Weight	366.42
Formula	C₂₃H₁₈N₄O
Cas No.	474379-42-5
Smiles	O=C1NC(NC=2C=CC=CC12)C3=CN(N=C3C=4C=CC=CC4)C=5C=CC=CC5

Storage & Solubility Information

Storage

keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 80 mg/mL (218.33 mM), Sonication is recommmended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.7291 mL	13.6455 mL	27.2911 mL	136.4554 mL
5 mM	0.5458 mL	2.7291 mL	5.4582 mL	27.2911 mL
10 mM	0.2729 mL	1.3646 mL	2.7291 mL	13.6455 mL
20 mM	0.1365 mL	0.6823 mL	1.3646 mL	6.8228 mL
50 mM	0.0546 mL	0.2729 mL	0.5458 mL	2.7291 mL
100 mM	0.0273 mL	0.1365 mL	0.2729 mL	1.3646 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc