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Volagidemab
🥰Excellent
Catalog No. T76876Cas No. 1233956-13-2
Alias REMD-477, REMD477, AMG-477, AMG477
Volagidemab (AMG-477) is a glucagon receptor (GCGR) antagonist and monoclonal antibody for the study of endocrine and metabolic diseases such as type 1 diabetes (T1D) and hypoglycemia.
Volagidemab
Volagidemab
🥰Excellent
Purity: 97.8% (SDS-PAGE); 98% (SEC-HPLC)
Catalog No. T76876Alias REMD-477, REMD477, AMG-477, AMG477Cas No. 1233956-13-2
Volagidemab (AMG-477) is a glucagon receptor (GCGR) antagonist and monoclonal antibody for the study of endocrine and metabolic diseases such as type 1 diabetes (T1D) and hypoglycemia.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $247 | In Stock | |
| 5 mg | $645 | In Stock | |
| 10 mg | $986 | In Stock | |
| 25 mg | $1,490 | In Stock | |
| 50 mg | $1,970 | In Stock |
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Concentration:6.72 mg/mL
Purity:97.8% (SDS-PAGE); 98% (SEC-HPLC)
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Product Introduction
Bioactivity
Chemical Properties
| Description | Volagidemab (AMG-477) is a glucagon receptor (GCGR) antagonist and monoclonal antibody for the study of endocrine and metabolic diseases such as type 1 diabetes (T1D) and hypoglycemia. |
| In vivo | Subcutaneous injection of 5 mg/kg Volagidemab suppresses the phenotype of type 1 diabetes in a mouse model of tetracycline-induced diabetes. [2] |
| Synonyms | REMD-477, REMD477, AMG-477, AMG477 |
| Cas No. | 1233956-13-2 |
| Color | Transparent |
| Appearance | Liquid |
Storage & Solubility Information
| Storage | store at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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