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Volagidemab (Synonyms: REMD-477, REMD477, AMG-477, AMG477)

Catalog No. T76876 Copy Product Info
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Volagidemab (AMG-477) is a glucagon receptor (GCGR) antagonist and monoclonal antibody for the study of endocrine and metabolic diseases such as type 1 diabetes (T1D) and hypoglycemia.

Volagidemab

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Catalog No. T76876
Synonyms REMD-477, REMD477, AMG-477, AMG477

Volagidemab (AMG-477) is a glucagon receptor (GCGR) antagonist and monoclonal antibody for the study of endocrine and metabolic diseases such as type 1 diabetes (T1D) and hypoglycemia.

Volagidemab
Cas No. 1233956-13-2
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Pack SizePriceUSA StockGlobal StockQuantity
1 mg$247In StockIn Stock
5 mg$645In StockIn Stock
10 mg$986-In Stock
25 mg$1,490-In Stock
50 mg$1,970-In Stock
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Batch Information

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Purity:97.8% (SDS-PAGE); 98% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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Product Introduction

Bioactivity
Description
Volagidemab (AMG-477) is a glucagon receptor (GCGR) antagonist and monoclonal antibody for the study of endocrine and metabolic diseases such as type 1 diabetes (T1D) and hypoglycemia.
In vivo
Subcutaneous injection of 5 mg/kg Volagidemab suppresses the phenotype of type 1 diabetes in a mouse model of tetracycline-induced diabetes. [2]
SynonymsREMD-477, REMD477, AMG-477, AMG477
Reactivity
Human
Application
Functional assay
Antibody Type
Monoclonal
FormulationSupplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Gene ID
Uniprot ID
TargetGCGR/GLR
Chemical Properties
Molecular Weight147 kDa
Cas No.1233956-13-2
Antibody Information
IsotypeHuman IgG2 kappa
Recommended Isotype Control
Storage & Solubility Information
StorageShipping with blue ice/Shipping at ambient temperature.

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