Powder: -20°C for 3 years | In solvent: -80°C for 1 year
FB49 is a selective Bcl-2-associated athanogene 3 (BAG3) inhibitor with a Ki of 45 μM. It inhibits the proliferation of human tumoral cells without affecting the viability of human peripheral mononuclear cells. Additionally, FB49 arrests the cell cycle at the G1 phase and induces apoptosis and autophagy in treated medulloblastoma HD-MB03 cells [1].
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Description | FB49 is a selective Bcl-2-associated athanogene 3 (BAG3) inhibitor with a Ki of 45 μM. It inhibits the proliferation of human tumoral cells without affecting the viability of human peripheral mononuclear cells. Additionally, FB49 arrests the cell cycle at the G1 phase and induces apoptosis and autophagy in treated medulloblastoma HD-MB03 cells [1]. |
Molecular Weight | 378.4 |
Formula | C17H18N2O6S |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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FB49 Autophagy inhibitor inhibit