Powder: -20°C for 3 years | In solvent: -80°C for 1 year
HL23 is a histone deacetylase (HDAC) inhibitor that effectively targets hepatocellular carcinoma (HCC). It promotes acetylation at the TXNIP promoter and increases TXNIP expression, which in turn modulates potassium channel activity and induces TXNIP-dependent potassium deficiency. Additionally, HL23 impedes the advancement and spread of HCC and demonstrates a synergistic effect when combined with Sorafenib, exhibiting greater potency than the duo of Sorafenib and Vorinostat [1].
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | Inquiry | $ 1,370.00 | |
50 mg | Inquiry | $ 2,780.00 | |
100 mg | Inquiry | $ 3,700.00 |
Description | HL23 is a histone deacetylase (HDAC) inhibitor that effectively targets hepatocellular carcinoma (HCC). It promotes acetylation at the TXNIP promoter and increases TXNIP expression, which in turn modulates potassium channel activity and induces TXNIP-dependent potassium deficiency. Additionally, HL23 impedes the advancement and spread of HCC and demonstrates a synergistic effect when combined with Sorafenib, exhibiting greater potency than the duo of Sorafenib and Vorinostat [1]. |
Molecular Weight | 712.83 |
Formula | C44H44N2O7 |
CAS No. | 1448355-15-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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HL23 1448355-15-4 Others inhibitor inhibit