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L-Homoserine lactone hydrochloride

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Catalog No. T38313Cas No. 2185-03-7

L-Homoserine lactone hydrochloride constitutes the core structural unit of N-acetylhomoserine lactone (AHL), a bacterial quorum sensing signal molecule.

L-Homoserine lactone hydrochloride
Other Forms of L-Homoserine lactone hydrochloride:
D-Homoserine lactoneT3639651744-82-2
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L-Homoserine lactone hydrochloride

🥰Excellent
Purity: 99.93%
Catalog No. T38313Cas No. 2185-03-7
L-Homoserine lactone hydrochloride constitutes the core structural unit of N-acetylhomoserine lactone (AHL), a bacterial quorum sensing signal molecule.
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1 g$29-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.93%
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COA HNMR LCMS

Product Introduction

Bioactivity
Description
L-Homoserine lactone hydrochloride constitutes the core structural unit of N-acetylhomoserine lactone (AHL), a bacterial quorum sensing signal molecule.
In vitro
L-Homoserine lactone hydrochloride is the metabolic product of AHLs processed by plant fatty acid amide hydrolase. The impact of AHLs on plant growth depends on whether they can be converted into this compound. The effect of AHLs on seedling growth exhibits concentration dependence: at low concentrations, it stimulates growth by promoting transpiration, whereas at high concentrations, it inhibits growth by inducing ethylene production [2].
Chemical Properties
Molecular Weight137.57
FormulaC4H8ClNO2
Cas No.2185-03-7
SmilesN[C@@H]1C(=O)OCC1.Cl
ColorWhite
AppearanceSolid
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
PBS (pH 7.2): 10 mg/mL (72.69 mM), Sonication is recommended.
DMSO: 80 mg/mL (581.52 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 1 mg/mL (7.27 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
PBS (pH 7.2)/DMSO
1mg5mg10mg50mg
1 mM7.2690 mL36.3451 mL72.6903 mL363.4513 mL
5 mM1.4538 mL7.2690 mL14.5381 mL72.6903 mL
10 mM0.7269 mL3.6345 mL7.2690 mL36.3451 mL
20 mM0.3635 mL1.8173 mL3.6345 mL18.1726 mL
50 mM0.1454 mL0.7269 mL1.4538 mL7.2690 mL
DMSO
1mg5mg10mg50mg
100 mM0.0727 mL0.3635 mL0.7269 mL3.6345 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
mg/kg
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2 Enter the in vivo formulation:
% DMSO
%
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% Saline/PBS/ddH2O

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

L-Homoserine lactone
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