Powder: -20°C for 3 years | In solvent: -80°C for 1 year
SLC26A3-IN-1 is an inhibitor of the anion-exchange protein SLC26A3 with an IC50 value of 340 nM.SLC26A3 is a solute carrier (SLC) protein and a member of the SLC26 family, which has a wide range of anionic specificities for chloride, bicarbonate, sulfate, and oxalate.SLC26A3 is downregulated in adenomas (DRA) and is involved in the intestinal absorption of chloride and oxalate and is associated with chloride-losing diarrhea. SLC26A3 is downregulated in adenomas (DRA), is involved in the intestinal absorption of chloride and oxalate, and is associated with chloride-losing diarrhea.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 195.00 | |
5 mg | In stock | $ 430.00 | |
10 mg | In stock | $ 636.00 | |
25 mg | In stock | $ 987.00 | |
50 mg | In stock | $ 1,360.00 | |
100 mg | In stock | $ 1,830.00 | |
500 mg | In stock | $ 3,680.00 |
Description | SLC26A3-IN-1 is an inhibitor of the anion-exchange protein SLC26A3 with an IC50 value of 340 nM.SLC26A3 is a solute carrier (SLC) protein and a member of the SLC26 family, which has a wide range of anionic specificities for chloride, bicarbonate, sulfate, and oxalate.SLC26A3 is downregulated in adenomas (DRA) and is involved in the intestinal absorption of chloride and oxalate and is associated with chloride-losing diarrhea. SLC26A3 is downregulated in adenomas (DRA), is involved in the intestinal absorption of chloride and oxalate, and is associated with chloride-losing diarrhea. |
Targets&IC50 | SLC26A3:340 Nm |
In vitro | SLC26A3-IN-1 (Compound 4a) (10 μM; 10 min) inhibitory rate on SLC26A3 is 87%.[1] |
Molecular Weight | 358.39 |
Formula | C23H18O4 |
CAS No. | 307552-53-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 50 mg/mL (139.5 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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SLC26A3-IN-1 307552-53-0 Metabolism transporter inhibitor inhibit