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Swertiamarin

Name: Swertiamarin
Brand: TargetMol
SKU: T2756
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T2756Cas No. 17388-39-5

Alias Swertiamaroside

Swertiamarin (Swertiamaroside) is a common secoiridoid found among the members of Gentianaceae with anti-inflammatory, anticancer, hypoglycemic and hypolipidemic activities.

Swertiamarin

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Purity: 99.82%

Catalog No. T2756Alias SwertiamarosideCas No. 17388-39-5

Swertiamarin (Swertiamaroside) is a common secoiridoid found among the members of Gentianaceae with anti-inflammatory, anticancer, hypoglycemic and hypolipidemic activities.

Pack Size	Price	USA Warehouse	Global Warehouse
5 mg	$30	In Stock	In Stock
10 mg	$37	In Stock	In Stock
25 mg	$56	In Stock	In Stock
50 mg	$78	In Stock	In Stock
100 mg	$113	In Stock	In Stock
500 mg	$273	Inquiry	Inquiry
1 mL x 10 mM (in DMSO)	$44	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Purity:99.82%

Color:White

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COA

Product Introduction

Swertiamarin AI Summary

Swertiamarin displays a range of biological activities, including antiplasmodial activity against chloroquine-resistant Plasmodium falciparum W2 with an IC50 value greater than 50.0 µg/mL, indicating its efficacy at relatively high concentrations. It also induces DNA re-replication in SW480 colon adenocarcinoma cells with a potency of 23109.3 nM. Furthermore, Swertiamarin exhibits antifungal properties against Candida albicans and Cryptococcus neoformans, as well as antibacterial activity against multiple strains including Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Acinetobacter baumannii, and methicillin-resistant Staphylococcus aureus (MRSA), with efficacy demonstrated through MIC values and inhibition percentage in specific assays..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	Swertiamarin (Swertiamaroside) is a common secoiridoid found among the members of Gentianaceae with anti-inflammatory, anticancer, hypoglycemic and hypolipidemic activities.
Synonyms	Swertiamaroside

Chemical Properties

Molecular Weight	374.34
Formula	C₁₆H₂₂O₁₀
Cas No.	17388-39-5
Smiles	OC[C@H]1O[C@@H](O[C@@H]2OC=C3C(=O)OCC[C@@]3(O)[C@H]2C=C)[C@H](O)[C@@H](O)[C@@H]1O
Relative Density.	1.57 g/cm3

Storage & Solubility Information

Storage

keep away from moisture,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (133.57 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (5.34 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.6714 mL	13.3568 mL	26.7137 mL	133.5684 mL
5 mM	0.5343 mL	2.6714 mL	5.3427 mL	26.7137 mL
10 mM	0.2671 mL	1.3357 mL	2.6714 mL	13.3568 mL
20 mM	0.1336 mL	0.6678 mL	1.3357 mL	6.6784 mL
50 mM	0.0534 mL	0.2671 mL	0.5343 mL	2.6714 mL
100 mM	0.0267 mL	0.1336 mL	0.2671 mL	1.3357 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc