Shopping Cart
Remove All
  • TargetMol
    Your shopping cart is currently empty

9(E),11(E)-12-nitro Conjugated Linoleic Acid

Copy Product Info
😃Good
Catalog No. T37270Cas No. 1515620-30-0

9(E),11(E)-12-nitro Conjugated linoleic acid (9(E),11(E)-12-nitro CLA) is a nitrated fatty acid. It is formed from 9(Z),11(E)-CLA upon exposure to acidified nitrite, peroxynitrite, gaseous nitrogen dioxide, or a combination of myeloperoxidase, hydrogen peroxide, and nitrite.1It is also formed in LPS-stimulated RAW 264.7 macrophages, an effect that can be reduced by the nitric oxide synthase (NOS) inhibitor L-NAME .29(E),11(E)-12-nitro CLA has been found in human plasma.

9(E),11(E)-12-nitro Conjugated Linoleic Acid

9(E),11(E)-12-nitro Conjugated Linoleic Acid

Copy Product Info
😃Good
Catalog No. T37270Cas No. 1515620-30-0
9(E),11(E)-12-nitro Conjugated linoleic acid (9(E),11(E)-12-nitro CLA) is a nitrated fatty acid. It is formed from 9(Z),11(E)-CLA upon exposure to acidified nitrite, peroxynitrite, gaseous nitrogen dioxide, or a combination of myeloperoxidase, hydrogen peroxide, and nitrite.1It is also formed in LPS-stimulated RAW 264.7 macrophages, an effect that can be reduced by the nitric oxide synthase (NOS) inhibitor L-NAME .29(E),11(E)-12-nitro CLA has been found in human plasma.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μg$13335 days35 days
100 μg$24635 days35 days
250 μg$56835 days35 days
500 μg$1,09035 days35 days
Add to Cart
Add to Quotation
In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Questions
TargetMol
View More

Resource Download

Product Introduction

Bioactivity
Description
9(E),11(E)-12-nitro Conjugated linoleic acid (9(E),11(E)-12-nitro CLA) is a nitrated fatty acid. It is formed from 9(Z),11(E)-CLA upon exposure to acidified nitrite, peroxynitrite, gaseous nitrogen dioxide, or a combination of myeloperoxidase, hydrogen peroxide, and nitrite.1It is also formed in LPS-stimulated RAW 264.7 macrophages, an effect that can be reduced by the nitric oxide synthase (NOS) inhibitor L-NAME .29(E),11(E)-12-nitro CLA has been found in human plasma.
Chemical Properties
Molecular Weight325.449
FormulaC18H31NO4
Cas No.1515620-30-0
SmilesCCCCCC\C(=C/C=C/CCCCCCCC(O)=O)N(=O)=O
Relative Density.1.016 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
Ethanol: 50 mg/mL (153.63 mM), Sonication is recommended.
DMF: 50 mg/mL (153.63 mM), Sonication is recommended.
DMSO: 50 mg/mL (153.63 mM), Sonication is recommended.
0.1 M Na2CO3: 1 mg/mL (3.07 mM), Sonication is recommended.
Solution Preparation Table
0.1 M Na2CO3/Ethanol/DMF/DMSO
1mg5mg10mg50mg
1 mM3.0727 mL15.3634 mL30.7268 mL153.6339 mL
Ethanol/DMF/DMSO
1mg5mg10mg50mg
5 mM0.6145 mL3.0727 mL6.1454 mL30.7268 mL
10 mM0.3073 mL1.5363 mL3.0727 mL15.3634 mL
20 mM0.1536 mL0.7682 mL1.5363 mL7.6817 mL
50 mM0.0615 mL0.3073 mL0.6145 mL3.0727 mL
100 mM0.0307 mL0.1536 mL0.3073 mL1.5363 mL

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Related Tags: buy 9(E),11(E)-12-nitro Conjugated Linoleic Acid | purchase 9(E),11(E)-12-nitro Conjugated Linoleic Acid | 9(E),11(E)-12-nitro Conjugated Linoleic Acid cost | order 9(E),11(E)-12-nitro Conjugated Linoleic Acid | 9(E),11(E)-12-nitro Conjugated Linoleic Acid chemical structure | 9(E),11(E)-12-nitro Conjugated Linoleic Acid formula | 9(E),11(E)-12-nitro Conjugated Linoleic Acid molecular weight