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RO5256390

Name: RO5256390
Brand: TargetMol
SKU: T12744
Price: 52 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T12744Cas No. 1043495-96-0

RO5256390 is a trace amine-associated receptor 1 (TAAR1) agonist, a highly conserved G-protein-coupled receptor that blocks psychostimulant-induced hyperarousal, and may be used in the study of neurological disorders.

RO5256390

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Purity: 96.96%

Catalog No. T12744Cas No. 1043495-96-0

Pack Size	Price	Availability	Quantity
2 mg	$52	In Stock
1 mL x 10 mM (in DMSO)	$98	5 days

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Batch Information

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Purity:96.96%

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COA

Product Introduction

Bioactivity

Description

Chemical Properties

Molecular Weight	218.29
Formula	C₁₃H₁₈N₂O
Cas No.	1043495-96-0
Smiles	[C@@H](C[C@@H]1N=C(N)OC1)(CC)C2=CC=CC=C2
Relative Density.	1.13 g/cm3 (Predicted)
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 30 mg/mL (137.43 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	4.5811 mL	22.9053 mL	45.8106 mL	229.0531 mL
5 mM	0.9162 mL	4.5811 mL	9.1621 mL	45.8106 mL
10 mM	0.4581 mL	2.2905 mL	4.5811 mL	22.9053 mL
20 mM	0.2291 mL	1.1453 mL	2.2905 mL	11.4527 mL
50 mM	0.0916 mL	0.4581 mL	0.9162 mL	4.5811 mL
100 mM	0.0458 mL	0.2291 mL	0.4581 mL	2.2905 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

RO-5256390RO5256390RO 5256390amine-associated receptor 1 (TAAR1)