Contact UsQuotation
Shopping Cart
Remove All
  • TargetMol
    Your shopping cart is currently empty
Proceed to checkoutContinue shopping
TOPBioactivityChemical infoStorage&SolubilityCalculator

5(6)-Carboxy-2′,7′-dichlorofluorescein diacetate

😃Good
Catalog No. T38123Cas No. 127770-45-0

5(6)-Carboxy-2',7'-dichlorofluorescein diacetate is an oxidant-sensitive and cell-permeable fluorescent probe.1Base hydrolysis of the ester bonds by intracellular esterases releases the acetate groups and the resulting compound, 5(6)-carboxy-2',7',-dichlorofluorescein, is oxidized by reactive oxygen species (ROS) and nitric oxide (NO) and displays excitation/emission maxima of 504 and 530 nm, respectively, which can be quantified as a measure of oxidant production.

5(6)-Carboxy-2′,7′-dichlorofluorescein diacetate

5(6)-Carboxy-2′,7′-dichlorofluorescein diacetate

😃Good
Catalog No. T38123Cas No. 127770-45-0
5(6)-Carboxy-2',7'-dichlorofluorescein diacetate is an oxidant-sensitive and cell-permeable fluorescent probe.1Base hydrolysis of the ester bonds by intracellular esterases releases the acetate groups and the resulting compound, 5(6)-carboxy-2',7',-dichlorofluorescein, is oxidized by reactive oxygen species (ROS) and nitric oxide (NO) and displays excitation/emission maxima of 504 and 530 nm, respectively, which can be quantified as a measure of oxidant production.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 mg$14335 days35 days
50 mg$22335 days35 days
100 mg$29635 days35 days
Add to Cart
Add to Quotation
In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Questions
TargetMol
View More

Resource Download

Product Introduction

Bioactivity
Description
5(6)-Carboxy-2',7'-dichlorofluorescein diacetate is an oxidant-sensitive and cell-permeable fluorescent probe.1Base hydrolysis of the ester bonds by intracellular esterases releases the acetate groups and the resulting compound, 5(6)-carboxy-2',7',-dichlorofluorescein, is oxidized by reactive oxygen species (ROS) and nitric oxide (NO) and displays excitation/emission maxima of 504 and 530 nm, respectively, which can be quantified as a measure of oxidant production.
Chemical Properties
Molecular Weight529.3
FormulaC25H14Cl2O9
Cas No.127770-45-0
SmilesCC(=O)Oc1cc2Oc3cc(OC(C)=O)c(Cl)cc3C3(OC(=O)c4cc(ccc34)C(O)=O)c2cc1Cl.CC(=O)Oc1cc2Oc3cc(OC(C)=O)c(Cl)cc3C3(OC(=O)c4ccc(cc34)C(O)=O)c2cc1Cl
Storage & Solubility Information
Storagekeep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMF: 30 mg/mL (56.68 mM), Sonication is recommended.
DMSO: 30 mg/mL (56.68 mM), Sonication is recommended.
Solution Preparation Table
DMF/DMSO
1mg5mg10mg50mg
1 mM1.8893 mL9.4464 mL18.8929 mL94.4644 mL
5 mM0.3779 mL1.8893 mL3.7786 mL18.8929 mL
10 mM0.1889 mL0.9446 mL1.8893 mL9.4464 mL
20 mM0.0945 mL0.4723 mL0.9446 mL4.7232 mL
50 mM0.0378 mL0.1889 mL0.3779 mL1.8893 mL

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

5(6)-Carboxy-2′,7′-dichlorofluorescein Diacetate5(6)Carboxy2′,7′dichlorofluorescein diacetate5(6)-Carboxy-2′,7′-dichlorofluorescein5(6) Carboxy 2′,7′ dichlorofluorescein diacetate
Related Tags: buy 5(6)-Carboxy-2′,7′-dichlorofluorescein diacetate | purchase 5(6)-Carboxy-2′,7′-dichlorofluorescein diacetate | 5(6)-Carboxy-2′,7′-dichlorofluorescein diacetate cost | order 5(6)-Carboxy-2′,7′-dichlorofluorescein diacetate | 5(6)-Carboxy-2′,7′-dichlorofluorescein diacetate chemical structure | 5(6)-Carboxy-2′,7′-dichlorofluorescein diacetate formula | 5(6)-Carboxy-2′,7′-dichlorofluorescein diacetate molecular weight
TargetMol | Logo

Copyright © 2015-2026 TargetMol Chemicals Inc. All Rights Reserved.