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CIA-1 hcl(452087-38-6 Free base)

Catalog No. T71534 CAS 1049691-47-5

CIA-1 inhibits the nuclear receptor COUP-TFII, with IC50s ranging from 1.2 μM to 7.6 μM in prostate cancer cell lines.CIA-1 inhibits the growth of a variety of prostate cancer cell lines in vitro and inhibits COUP-TFII activity to regulate its target genes.CIA-1 in vivo exhibits tumor growth inhibitory effects in a mouse model of prostate cancer xenografts. inhibitory effect on tumor growth in a xenograft mouse model of prostate cancer in vivo.

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CIA-1 hcl(452087-38-6 Free base) Chemical Structure

CIA-1 hcl(452087-38-6 Free base), CAS 1049691-47-5

Pack Size	Availability	Price/USD	Quantity
10 mg	35 days	$ 393.00
50 mg	35 days	$ 1,640.00

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Purity: 99.02%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Molecular Weight	365.88
Formula	C17H20ClN3O2S
CAS No.	1049691-47-5

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 6.6 mg/mL (18.0 mM)

References and Literature

1. Renshaw RW, et al. A hypervariable region in VP1 of chicken infectious anemia virus mediates rate of spread and cell tropism in tissue culture. J Virol. 1996;70(12):8872-8878. 2. Matsumoto T, et al. Characterization of CIA-1, an Ambler class A extended-spectrum β-lactamase from Chryseobacterium indologenes. Antimicrob Agents Chemother. 2012;56(1):588-590.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

CIA-1 hcl(452087-38-6 Free base) 1049691-47-5 Neuroscience Proteases/Proteasome Stem Cells Gamma-secretase Mdl28815 Mdl-28815 inhibitor inhibit

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