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Tiafenacil

Name: Tiafenacil
Brand: TargetMol
SKU: T35866
Rating: 4.5 (1 reviews)

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Catalog No. T35866Cas No. 1220411-29-9

Tiafenacil is a novel herbicide that inhibits protoporphyrinogen IX oxidase (PPO), exhibiting IC50 values ranging from 22 to 28 nM across different plant species such as amaranth (Amaranthus tuberculatus), soybean (Glycine max), arabidopsis (Arabidopsis thaliana), and rapeseed (Brassica napus)[1].

Tiafenacil

🥰Excellent

Catalog No. T35866Cas No. 1220411-29-9

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Product Introduction

Bioactivity

Description	Tiafenacil is a novel herbicide that inhibits protoporphyrinogen IX oxidase (PPO), exhibiting IC50 values ranging from 22 to 28 nM across different plant species such as amaranth (Amaranthus tuberculatus), soybean (Glycine max), arabidopsis (Arabidopsis thaliana), and rapeseed (Brassica napus)[1].
In vitro	Tiafenacil exhibits low acute toxicity via oral and dermal exposure[1]. In velvetleaf, it induces significant growth inhibition at 1 μM and leads to desiccation and death at 5 μM[1].

Chemical Properties

Molecular Weight	511.87
Formula	C₁₉H₁₈ClF₄N₃O₅S
Cas No.	1220411-29-9
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 100 mg/mL (195.36 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween-80+45% Saline: 3.3 mg/mL (6.45 mM), Sonication is recommeded.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.9536 mL	9.7681 mL	19.5362 mL	97.6811 mL
5 mM	0.3907 mL	1.9536 mL	3.9072 mL	19.5362 mL
10 mM	0.1954 mL	0.9768 mL	1.9536 mL	9.7681 mL
20 mM	0.0977 mL	0.4884 mL	0.9768 mL	4.8841 mL
50 mM	0.0391 mL	0.1954 mL	0.3907 mL	1.9536 mL
100 mM	0.0195 mL	0.0977 mL	0.1954 mL	0.9768 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Tiafenacil