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Astragaloside I

Name: Astragaloside I
Brand: TargetMol
SKU: T3925
Price: 47 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T3925Cas No. 84680-75-1

Alias Cyclosieversioside B, Astrasieversianin IV

Astragaloside I (Cyclosieversioside B) is a natural product isolated from Astragalus membranaceus. It can stimulate osteoblast differentiation through the Wnt/β-catenin signaling pathway and can be used to study osteogenic activity.

Astragaloside I

🥰Excellent

Purity: 99.64%

Catalog No. T3925Alias Cyclosieversioside B, Astrasieversianin IVCas No. 84680-75-1

Pack Size	Price	Availability
5 mg	$47	In Stock
10 mg	$80	In Stock
25 mg	$163	In Stock
50 mg	$263	In Stock
100 mg	$447	In Stock
500 mg	$998	In Stock
1 mL x 10 mM (in DMSO)	$77	In Stock

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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.64%

Resource Download

COA HNMR HPLC

Product Introduction

Bioactivity

Description	Astragaloside I (Cyclosieversioside B) is a natural product isolated from Astragalus membranaceus. It can stimulate osteoblast differentiation through the Wnt/β-catenin signaling pathway and can be used to study osteogenic activity.
Synonyms	Cyclosieversioside B, Astrasieversianin IV

Chemical Properties

Molecular Weight	869.04
Formula	C₄₅H₇₂O₁₆
Cas No.	84680-75-1
Smiles	CC(=O)O[C@H]1[C@H](O)CO[C@@H](O[C@H]2CC[C@]34C[C@]33CC[C@]5(C)[C@H]([C@@H](O)C[C@@]5(C)[C@@H]3C[C@H](O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)[C@H]4C2(C)C)[C@@]2(C)CC[C@H](O2)C(C)(C)O)[C@@H]1OC(C)=O
Relative Density.	1.39 g/cm3
Color	Yellow
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 55 mg/mL (63.29 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2.5 mg/mL (2.88 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.1507 mL	5.7535 mL	11.5070 mL	57.5348 mL
5 mM	0.2301 mL	1.1507 mL	2.3014 mL	11.5070 mL
10 mM	0.1151 mL	0.5753 mL	1.1507 mL	5.7535 mL
20 mM	0.0575 mL	0.2877 mL	0.5753 mL	2.8767 mL
50 mM	0.0230 mL	0.1151 mL	0.2301 mL	1.1507 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc